Severe interstitial pneumonia induced by paclitaxel in a patient with adenocarcinoma of the lung

Noriyuki Suzaki; Akio Hiraki; Nagio Takigawa; Hiroshi Ueoka; Yasushi Tanimoto; Toshiyuki Kozuki; Masahiro Tabata; Arihiko Kanehiro; Katsuyuki Kiura; Mitsune Tanimoto

Severe interstitial pneumonia induced by paclitaxel in a patient with adenocarcinoma of the lung

Noriyuki Suzaki, Akio Hiraki, Nagio Takigawa, Hiroshi Ueoka, Yasushi Tanimoto, Toshiyuki Kozuki, Masahiro Tabata, Arihiko Kanehiro, Katsuyuki Kiura, Mitsune Tanimoto

University Hospital

Research output: Contribution to journal › Article › peer-review

13 Citations (Scopus)

Abstract

A 71-year-old Japanese man with adenocarcinoma of the lung developed interstitial pneumonia after treatment with paclitaxel. The patient had acute chills and fever on the fourth day after the second exposure to paclitaxel, rapidly got worse despite empiric therapies, and developed prolonged respiratory failure requiring mechanical ventilation. Four months later, he died of respiratory failure due to progression of both interstitial pneumonia and lung cancer. This is the first case developing fatal paclitaxel-induced pulmonary toxicity to date. Interstitial pneumonia should be considered one of the possible life-threatening complications during treatment with paclitaxel. Copyright

Original language	English
Pages (from-to)	295-298
Number of pages	4
Journal	Acta medica Okayama
Volume	60
Issue number	5
Publication status	Published - Oct 2006

Keywords

Adverse effect
Interstitial pneumonia
Lung cancer
Paclitaxel

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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abstract = "A 71-year-old Japanese man with adenocarcinoma of the lung developed interstitial pneumonia after treatment with paclitaxel. The patient had acute chills and fever on the fourth day after the second exposure to paclitaxel, rapidly got worse despite empiric therapies, and developed prolonged respiratory failure requiring mechanical ventilation. Four months later, he died of respiratory failure due to progression of both interstitial pneumonia and lung cancer. This is the first case developing fatal paclitaxel-induced pulmonary toxicity to date. Interstitial pneumonia should be considered one of the possible life-threatening complications during treatment with paclitaxel. Copyright",

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AU - Suzaki, Noriyuki

AU - Hiraki, Akio

AU - Takigawa, Nagio

AU - Ueoka, Hiroshi

AU - Tanimoto, Yasushi

AU - Kozuki, Toshiyuki

AU - Tabata, Masahiro

AU - Kanehiro, Arihiko

AU - Kiura, Katsuyuki

AU - Tanimoto, Mitsune

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N2 - A 71-year-old Japanese man with adenocarcinoma of the lung developed interstitial pneumonia after treatment with paclitaxel. The patient had acute chills and fever on the fourth day after the second exposure to paclitaxel, rapidly got worse despite empiric therapies, and developed prolonged respiratory failure requiring mechanical ventilation. Four months later, he died of respiratory failure due to progression of both interstitial pneumonia and lung cancer. This is the first case developing fatal paclitaxel-induced pulmonary toxicity to date. Interstitial pneumonia should be considered one of the possible life-threatening complications during treatment with paclitaxel. Copyright

AB - A 71-year-old Japanese man with adenocarcinoma of the lung developed interstitial pneumonia after treatment with paclitaxel. The patient had acute chills and fever on the fourth day after the second exposure to paclitaxel, rapidly got worse despite empiric therapies, and developed prolonged respiratory failure requiring mechanical ventilation. Four months later, he died of respiratory failure due to progression of both interstitial pneumonia and lung cancer. This is the first case developing fatal paclitaxel-induced pulmonary toxicity to date. Interstitial pneumonia should be considered one of the possible life-threatening complications during treatment with paclitaxel. Copyright

KW - Adverse effect

KW - Interstitial pneumonia

KW - Lung cancer

KW - Paclitaxel

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Severe interstitial pneumonia induced by paclitaxel in a patient with adenocarcinoma of the lung

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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