TY - JOUR
T1 - Sinus node function in patients with Brugada-type ECG
AU - Morita, Hiroshi
AU - Fukushima-Kusano, Kengo
AU - Nagase, Satoshi
AU - Miyaji, Kohei
AU - Hiramatsu, Shigeki
AU - Banba, Kimikazu
AU - Nishii, Nobuhiro
AU - Watanabe, Atsuyuki
AU - Kakishita, Mikio
AU - Takenaka-Morita, Shiho
AU - Nakamura, Kazufumi
AU - Saito, Hironori
AU - Emori, Tetsuro
AU - Ohe, Tohru
PY - 2004/5
Y1 - 2004/5
N2 - Background: Some studies have shown that patients with Brugada syndrome (BS) have atrioventricular conduction disturbance, but their sinus node function has not been evaluated. Methods and Results: The patients group consisted of 59 male patients and 1 female patient with BS. Supraventricular and ventricular programmed electrical stimulation (PES) was performed. Ventricular fibrillation (VF) or sustained polymorphic ventricular tachycardia was induced by ventricular PES in 26 patients with BS (VF group), but was not induced in the other 34 patients (non-VF group). Sinus node function and conduction of the atrioventricular (AV) node in the control group, nort-VF group and VF group were evaluated. Sinus node function was attenuated and the His-ventricle interval was prolonged in the VF group (corrected sinus node recovery time: 452±126 ms (VF group), 324±146 ms (non-VF group), Sino-atrial conduction time: 179±60 ms (VF group), 127±60 ms (non-VF group), His-ventricle interval: 41±9 ms (VF group), 35±8 ms (non-VF group)). Conclusion: The function of both the sinus node and AV node are attenuated in patients with PES-induced VF.
AB - Background: Some studies have shown that patients with Brugada syndrome (BS) have atrioventricular conduction disturbance, but their sinus node function has not been evaluated. Methods and Results: The patients group consisted of 59 male patients and 1 female patient with BS. Supraventricular and ventricular programmed electrical stimulation (PES) was performed. Ventricular fibrillation (VF) or sustained polymorphic ventricular tachycardia was induced by ventricular PES in 26 patients with BS (VF group), but was not induced in the other 34 patients (non-VF group). Sinus node function and conduction of the atrioventricular (AV) node in the control group, nort-VF group and VF group were evaluated. Sinus node function was attenuated and the His-ventricle interval was prolonged in the VF group (corrected sinus node recovery time: 452±126 ms (VF group), 324±146 ms (non-VF group), Sino-atrial conduction time: 179±60 ms (VF group), 127±60 ms (non-VF group), His-ventricle interval: 41±9 ms (VF group), 35±8 ms (non-VF group)). Conclusion: The function of both the sinus node and AV node are attenuated in patients with PES-induced VF.
KW - AV node function
KW - Brugada
KW - Sinus node function
KW - Sinus node recovery time
KW - Syndrome
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U2 - 10.1253/circj.68.473
DO - 10.1253/circj.68.473
M3 - Article
C2 - 15118291
AN - SCOPUS:2442695037
SN - 1346-9843
VL - 68
SP - 473
EP - 476
JO - Circulation Journal
JF - Circulation Journal
IS - 5
ER -