TY - JOUR
T1 - Sirolimus Ameliorated Post Lung Transplant Chylothorax in Lymphangioleiomyomatosis
AU - Ohara, Toshiaki
AU - Oto, Takahiro
AU - Miyoshi, Kentaro
AU - Tao, Hiroyuki
AU - Yamane, Masaomi
AU - Toyooka, Shinichi
AU - Okazaki, Megumi
AU - Date, Hiroshi
AU - Sano, Yoshifumi
PY - 2008/12
Y1 - 2008/12
N2 - We report a successful case of sirolimus treatment for chylous pleural and peritoneal effusions of lymphangioleiomyomatosis after lung transplantation. A 32-year-old woman underwent living donor lung transplantation. Persistent chylous pleural and peritoneal effusions were seen postoperatively. Pleurodesis by intrathoracic injection of OK-432, minomycin, and somatostatine analog failed to control chylous effusions. However, sirolimus treatment reduced the amount of chylous drainage and improved both chylous pleural and peritoneal effusions.
AB - We report a successful case of sirolimus treatment for chylous pleural and peritoneal effusions of lymphangioleiomyomatosis after lung transplantation. A 32-year-old woman underwent living donor lung transplantation. Persistent chylous pleural and peritoneal effusions were seen postoperatively. Pleurodesis by intrathoracic injection of OK-432, minomycin, and somatostatine analog failed to control chylous effusions. However, sirolimus treatment reduced the amount of chylous drainage and improved both chylous pleural and peritoneal effusions.
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U2 - 10.1016/j.athoracsur.2008.07.062
DO - 10.1016/j.athoracsur.2008.07.062
M3 - Article
C2 - 19021963
AN - SCOPUS:56049110857
SN - 0003-4975
VL - 86
SP - e7-e8
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 6
ER -