Spectrophotometric determination of quinine and its related drugs with o-sulfophenylfluorone and copper(II)

Chikako Yamazaki; Hiroshi Tominaga; Megumi Samma; Rie Isono; Shinichiro Kamino; Takako Yamaguchi; Yoshikazu Fujita

doi:10.2116/bunsekikagaku.56.879

Spectrophotometric determination of quinine and its related drugs with o-sulfophenylfluorone and copper(II)

Chikako Yamazaki, Hiroshi Tominaga, Megumi Samma, Rie Isono, Shinichiro Kamino, Takako Yamaguchi, Yoshikazu Fujita

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

A novel spectrophotometric method was established for the determination of quinine and its related drugs based on ternary complex formation among o-sulfophenylfluorone, copper(II) and quinine. In the determination of quinine, Beer's low is obeyed in the range of 0.2-3.2 μg cm ^-3. The effective molar absorptivity at 590 nm and the relative standard deviation were 2.0×10 ⁵ dm ³ mol ^-1 cm ^-1 and 2.0% (n = 6), respectively. The method was successfully applied to assays of quinine and its related drugs in pharmaceutical preparations. In addition, it was suggested that the ternary complex showed thermochromism.

Original language	English
Pages (from-to)	879-884
Number of pages	6
Journal	BUNSEKI KAGAKU
Volume	56
Issue number	10
DOIs	https://doi.org/10.2116/bunsekikagaku.56.879
Publication status	Published - 2007
Externally published	Yes

Keywords

Quinine and its related drugs
Spectrophotometry
Ternary complex
Thermochromism
o-sulfophenylfluorone and copper(II)

ASJC Scopus subject areas

Analytical Chemistry

Access to Document

10.2116/bunsekikagaku.56.879

Cite this

@article{b08b3a7b6e2f499c8fb911306fb57f12,

title = "Spectrophotometric determination of quinine and its related drugs with o-sulfophenylfluorone and copper(II)",

abstract = "A novel spectrophotometric method was established for the determination of quinine and its related drugs based on ternary complex formation among o-sulfophenylfluorone, copper(II) and quinine. In the determination of quinine, Beer's low is obeyed in the range of 0.2-3.2 μg cm -3. The effective molar absorptivity at 590 nm and the relative standard deviation were 2.0×10 5 dm 3 mol -1 cm -1 and 2.0% (n = 6), respectively. The method was successfully applied to assays of quinine and its related drugs in pharmaceutical preparations. In addition, it was suggested that the ternary complex showed thermochromism.",

keywords = "Quinine and its related drugs, Spectrophotometry, Ternary complex, Thermochromism, o-sulfophenylfluorone and copper(II)",

author = "Chikako Yamazaki and Hiroshi Tominaga and Megumi Samma and Rie Isono and Shinichiro Kamino and Takako Yamaguchi and Yoshikazu Fujita",

year = "2007",

doi = "10.2116/bunsekikagaku.56.879",

language = "English",

volume = "56",

pages = "879--884",

journal = "Bunseki Kagaku",

issn = "0525-1931",

publisher = "Japan Society for Analytical Chemistry",

number = "10",

}

TY - JOUR

T1 - Spectrophotometric determination of quinine and its related drugs with o-sulfophenylfluorone and copper(II)

AU - Yamazaki, Chikako

AU - Tominaga, Hiroshi

AU - Samma, Megumi

AU - Isono, Rie

AU - Kamino, Shinichiro

AU - Yamaguchi, Takako

AU - Fujita, Yoshikazu

PY - 2007

Y1 - 2007

N2 - A novel spectrophotometric method was established for the determination of quinine and its related drugs based on ternary complex formation among o-sulfophenylfluorone, copper(II) and quinine. In the determination of quinine, Beer's low is obeyed in the range of 0.2-3.2 μg cm -3. The effective molar absorptivity at 590 nm and the relative standard deviation were 2.0×10 5 dm 3 mol -1 cm -1 and 2.0% (n = 6), respectively. The method was successfully applied to assays of quinine and its related drugs in pharmaceutical preparations. In addition, it was suggested that the ternary complex showed thermochromism.

AB - A novel spectrophotometric method was established for the determination of quinine and its related drugs based on ternary complex formation among o-sulfophenylfluorone, copper(II) and quinine. In the determination of quinine, Beer's low is obeyed in the range of 0.2-3.2 μg cm -3. The effective molar absorptivity at 590 nm and the relative standard deviation were 2.0×10 5 dm 3 mol -1 cm -1 and 2.0% (n = 6), respectively. The method was successfully applied to assays of quinine and its related drugs in pharmaceutical preparations. In addition, it was suggested that the ternary complex showed thermochromism.

KW - Quinine and its related drugs

KW - Spectrophotometry

KW - Ternary complex

KW - Thermochromism

KW - o-sulfophenylfluorone and copper(II)

UR - http://www.scopus.com/inward/record.url?scp=36949013415&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=36949013415&partnerID=8YFLogxK

U2 - 10.2116/bunsekikagaku.56.879

DO - 10.2116/bunsekikagaku.56.879

M3 - Article

AN - SCOPUS:36949013415

SN - 0525-1931

VL - 56

SP - 879

EP - 884

JO - Bunseki Kagaku

JF - Bunseki Kagaku

IS - 10

ER -

Spectrophotometric determination of quinine and its related drugs with o-sulfophenylfluorone and copper(II)

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this