Spontaneous regression of malignant pleural mesothelioma

Rika Kawanishi, Hiroshi Ueoka, Masahiro Tabata, Takuo Shibayama, Tomofumi Yano, Akio Matsushita, Kenichi Chikamori, Hiroyuki Kohara, Mine Harada, Taisuke Ohnoshi

Research output: Contribution to journalArticlepeer-review

3 Citations (Scopus)


We describe the spontaneous regression of a malignant pleural mesothelioma with left pleural effusion, chest pain, and a high fever (38° to 39°C) in a 37-year-old man. The patient was referred to us because multiple nodules were seen on his chest radiograph after he was successfully treated with thoracocentesis and conventional antibiotic therapy for pleural effusion. Our diagnosis was malignant pleural mesothelioma, based on histologic findings in a biopsy specimen obtained during thoracoscopy. Interestingly, the tumors markedly regressed without treatment, and the patient was doing well more than 5 months after the cancer was diagnosed. The spontaneous regression of malignant pleural mesothelioma is rare, and this may represent the first case report.

Original languageEnglish
Pages (from-to)118-120
Number of pages3
JournalInternational Journal of Clinical Oncology
Issue number2
Publication statusPublished - 1997


  • Malignant mesothelioma
  • Spontaneous regression
  • Thoracoscopy

ASJC Scopus subject areas

  • Surgery
  • Hematology
  • Oncology


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