Spontaneous rupture of a hepatic angiomyolipoma: Report of a case

Hideki Aoki, Takashi Arata, Toshiaki Morihiro, Nobuhiko Kanaya, Sho Takeda, Kenta Sui, Kunitoshi Shigeyasu, Koh Katsuda, Kohji Tanakaya, Hitoshi Takeuchi

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


A 70-year-old female experienced sudden onset of back pain on the right side and was admitted to our hospital in December 2010. Abdominal computed tomography revealed an S7 hepatic mass measuring 7 cm in diameter accompanied by a subcapsular hematoma. Emergency angiography confirmed the diagnosis of a ruptured hepatic mass, and hemostasis was carried out by embolization of A8 and A7 of the liver. A right hepatic lobectomy was carried out 39 days following transarterial embolization. Although almost all aspects of the tumor were necrotic, residual tumor cells stained positive for HMB-45, and negative for α-SMA, S-100, CD 34, c-kit, CAM 5.2, and hepatocytes. The MIB-1 index was 2 %. Pathological diagnosis was hepatic angiomyolipoma (HAML). The patient has shown no signs of recurrence at 42 months following surgery. Here, we report on this case of spontaneous HAML rupture and discuss therapeutic strategies for HAML and ruptured hepatic tumors.

Original languageEnglish
Pages (from-to)429-433
Number of pages5
JournalClinical Journal of Gastroenterology
Issue number5
Publication statusPublished - Oct 8 2014
Externally publishedYes


  • HMB-45
  • Hepatic angiomyolipoma
  • Rupture

ASJC Scopus subject areas

  • Gastroenterology


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