Spray Pyrolysis Preparation of Apatite-Composite Particles for Biological Application

Akiyoshi Osaka, Kanji Tsuru, H. Iida, Chikara Ohtsuki, Satoshi Hayakawa, Yoshinari Miura

Research output: Contribution to journalArticlepeer-review

11 Citations (Scopus)


Apatite derived by sol-gel routes through an amorphous state or derived biomimetically is likely to provide chemically and biologically active surfaces. Thus apatite or apatite-composite particles were prepared by spray-pyrolysis of several solutions as they were applicable to medical treatment. Calcium lactate and ammonium dihydrogen phosphate aqueous solutions stabilized with ethylenediaminetetraacetic acid were sprayed ultrasonically and pyrolysed at 600°C to yield amorphous particles of apatite while apatite-ferric oxide composite powders were prepared from the solutions of calcium lactate and ferric nitrate. Solutions of calcium nitrate and titanium ethoxide in 0.5 N HNO3 were also spray-pyrolysed at 600°C to prepare calcium titanate and titanium oxide particles trapped on a Ti substrate. Apatite could biomimetically be developed on the calcium titanate particles when they were soaked in an acellular simulated body fluid.

Original languageEnglish
Pages (from-to)655-661
Number of pages7
JournalJournal of Sol-Gel Science and Technology
Issue number1-3
Publication statusPublished - 1997


  • Apatite
  • Biomimetic deposition
  • Composite particle
  • Spray pyrolysis

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • General Chemistry
  • Biomaterials
  • Condensed Matter Physics
  • Materials Chemistry


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