TY - JOUR
T1 - Stereochemistry of enacyloxins 2. Structure elucidation of decarbamoyl enacyloxin IIa and IVa, new members of enacyloxin antibiotics from Frateuria sp. W-315
AU - Watanabe, Toshihiko
AU - Kiyota, Hiromasa
AU - Takeuchi, Ryo
AU - Enari, Keijiro
AU - Oritani, Takayuki
PY - 2001/1/1
Y1 - 2001/1/1
N2 - Two new members of enacyloxins (ENXs) were isolated from the culture extract of Frateuria sp. W-315. Spectrometric analyses revealed their structures as decarbamoyl enacyloxin IVa and IIa, the latter preferentially existed in the hemiacetal form. Formation of these compounds were catalyzed by enzymes produced by the fungus. From the coupling constant values of the hemiacetal part of dec ENX IIa, the (17′R*, 18′S*, 19′R*) relative configuration of ENXs was also elucidated.
AB - Two new members of enacyloxins (ENXs) were isolated from the culture extract of Frateuria sp. W-315. Spectrometric analyses revealed their structures as decarbamoyl enacyloxin IVa and IIa, the latter preferentially existed in the hemiacetal form. Formation of these compounds were catalyzed by enzymes produced by the fungus. From the coupling constant values of the hemiacetal part of dec ENX IIa, the (17′R*, 18′S*, 19′R*) relative configuration of ENXs was also elucidated.
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U2 - 10.1515/HC.2001.7.4.313
DO - 10.1515/HC.2001.7.4.313
M3 - Article
AN - SCOPUS:0035730856
SN - 0793-0283
VL - 7
SP - 313
EP - 316
JO - Heterocyclic Communications
JF - Heterocyclic Communications
IS - 4
ER -