Stereoselective synthesis of (E)-ArCFCFR and (E)-ArCHCFR from ArCH(OH)CFBr2

Manabu Kuroboshi; Nobuko Yamada; Yoko Takebe; Tamejiro Hiyama

doi:10.1016/0040-4039(95)01257-I

Stereoselective synthesis of (E)-ArCFCFR and (E)-ArCHCFR from ArCH(OH)CFBr₂

Manabu Kuroboshi, Nobuko Yamada, Yoko Takebe, Tamejiro Hiyama

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

(E)-vic-Difluoro olefin, RCFCFBr, was synthesized by dehydrobromination of RCFHCFBr₂ using lithium 2,2,6,6-tetramethylpiperidide. (E)-Fluoro olefin, RCHCFBr, was obtained by treatment of RCH(OAc)CFBr₂ with EtMgBr and HN(i-Pr)₂.

Original language	English
Pages (from-to)	6271-6274
Number of pages	4
Journal	Tetrahedron Letters
Volume	36
Issue number	35
DOIs	https://doi.org/10.1016/0040-4039(95)01257-I
Publication status	Published - Aug 28 1995
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Stereoselective synthesis of (E)-ArCFCFR and (E)-ArCHCFR from ArCH(OH)CFBr2",

abstract = "(E)-vic-Difluoro olefin, RCFCFBr, was synthesized by dehydrobromination of RCFHCFBr2 using lithium 2,2,6,6-tetramethylpiperidide. (E)-Fluoro olefin, RCHCFBr, was obtained by treatment of RCH(OAc)CFBr2 with EtMgBr and HN(i-Pr)2.",

author = "Manabu Kuroboshi and Nobuko Yamada and Yoko Takebe and Tamejiro Hiyama",

year = "1995",

month = aug,

day = "28",

doi = "10.1016/0040-4039(95)01257-I",

language = "English",

volume = "36",

pages = "6271--6274",

journal = "Tetrahedron Letters",

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number = "35",

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T1 - Stereoselective synthesis of (E)-ArCFCFR and (E)-ArCHCFR from ArCH(OH)CFBr2

AU - Kuroboshi, Manabu

AU - Yamada, Nobuko

AU - Takebe, Yoko

AU - Hiyama, Tamejiro

PY - 1995/8/28

Y1 - 1995/8/28

N2 - (E)-vic-Difluoro olefin, RCFCFBr, was synthesized by dehydrobromination of RCFHCFBr2 using lithium 2,2,6,6-tetramethylpiperidide. (E)-Fluoro olefin, RCHCFBr, was obtained by treatment of RCH(OAc)CFBr2 with EtMgBr and HN(i-Pr)2.

AB - (E)-vic-Difluoro olefin, RCFCFBr, was synthesized by dehydrobromination of RCFHCFBr2 using lithium 2,2,6,6-tetramethylpiperidide. (E)-Fluoro olefin, RCHCFBr, was obtained by treatment of RCH(OAc)CFBr2 with EtMgBr and HN(i-Pr)2.

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U2 - 10.1016/0040-4039(95)01257-I

DO - 10.1016/0040-4039(95)01257-I

M3 - Article

AN - SCOPUS:0029161698

SN - 0040-4039

VL - 36

SP - 6271

EP - 6274

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 35

ER -

Stereoselective synthesis of (E)-ArCFCFR and (E)-ArCHCFR from ArCH(OH)CFBr₂

Abstract

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