Structural determination of a new 2(3 → 20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane from Taxus cuspidata

Changhong Huo; Xiaohui Su; Xing Li; Xiping Zhang; Cunfang Li; Yufang Wang; Qingwen Shi; Hiromasa Kiyota

doi:10.1002/mrc.2001

Structural determination of a new 2(3 → 20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane from Taxus cuspidata

Changhong Huo, Xiaohui Su, Xing Li, Xiping Zhang, Cunfang Li, Yufang Wang, Qingwen Shi, Hiromasa Kiyota

Research output: Contribution to journal › Article › peer-review

7 Citations (Scopus)

Abstract

A new 2(3 → 20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane were isolated from the methanol extract of the needles of Taxus cuspidata. The structures were established as 2α,7β-diacetoxy-5α,10β,13β-trihydroxy-2(3 → 20)abeotaxa-4(20), 11-dien-9-one (1) and 2α,5α,7β,9α, 13α-pentahydroxy-10β-acetoxytaxa-4(20),11-diene (2) on the basis of 1D and 2D NMR spectral data and high-resolution FAB-MS analyses.

Original language	English
Pages (from-to)	527-530
Number of pages	4
Journal	Magnetic Resonance in Chemistry
Volume	45
Issue number	6
DOIs	https://doi.org/10.1002/mrc.2001
Publication status	Published - Jun 1 2007
Externally published	Yes

Keywords

2D NMR
2α,7β-diacetoxy-5α,10β,13β- trihydroxy-2(3 → 20)abeotaxa-4(20), 11-dien-9-one, 2α,5α, 7β,9α,13α-pentahydroxy-10β-acetoxytaxa-4(20), 11-diene
NMR
Taxaceae
Taxus cuspidata

ASJC Scopus subject areas

Chemistry(all)
Materials Science(all)

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10.1002/mrc.2001

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title = "Structural determination of a new 2(3 → 20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane from Taxus cuspidata",

abstract = "A new 2(3 → 20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane were isolated from the methanol extract of the needles of Taxus cuspidata. The structures were established as 2α,7β-diacetoxy-5α,10β,13β-trihydroxy-2(3 → 20)abeotaxa-4(20), 11-dien-9-one (1) and 2α,5α,7β,9α, 13α-pentahydroxy-10β-acetoxytaxa-4(20),11-diene (2) on the basis of 1D and 2D NMR spectral data and high-resolution FAB-MS analyses.",

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author = "Changhong Huo and Xiaohui Su and Xing Li and Xiping Zhang and Cunfang Li and Yufang Wang and Qingwen Shi and Hiromasa Kiyota",

year = "2007",

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doi = "10.1002/mrc.2001",

language = "English",

volume = "45",

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T1 - Structural determination of a new 2(3 → 20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane from Taxus cuspidata

AU - Huo, Changhong

AU - Su, Xiaohui

AU - Li, Xing

AU - Zhang, Xiping

AU - Li, Cunfang

AU - Wang, Yufang

AU - Shi, Qingwen

AU - Kiyota, Hiromasa

PY - 2007/6/1

Y1 - 2007/6/1

N2 - A new 2(3 → 20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane were isolated from the methanol extract of the needles of Taxus cuspidata. The structures were established as 2α,7β-diacetoxy-5α,10β,13β-trihydroxy-2(3 → 20)abeotaxa-4(20), 11-dien-9-one (1) and 2α,5α,7β,9α, 13α-pentahydroxy-10β-acetoxytaxa-4(20),11-diene (2) on the basis of 1D and 2D NMR spectral data and high-resolution FAB-MS analyses.

AB - A new 2(3 → 20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane were isolated from the methanol extract of the needles of Taxus cuspidata. The structures were established as 2α,7β-diacetoxy-5α,10β,13β-trihydroxy-2(3 → 20)abeotaxa-4(20), 11-dien-9-one (1) and 2α,5α,7β,9α, 13α-pentahydroxy-10β-acetoxytaxa-4(20),11-diene (2) on the basis of 1D and 2D NMR spectral data and high-resolution FAB-MS analyses.

KW - 2D NMR

KW - 2α,7β-diacetoxy-5α,10β,13β- trihydroxy-2(3 → 20)abeotaxa-4(20), 11-dien-9-one, 2α,5α, 7β,9α,13α-pentahydroxy-10β-acetoxytaxa-4(20), 11-diene

KW - NMR

KW - Taxaceae

KW - Taxus cuspidata

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SN - 0749-1581

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EP - 530

JO - Magnetic Resonance in Chemistry

JF - Magnetic Resonance in Chemistry

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ER -

Structural determination of a new 2(3 → 20)abeotaxane with an unusual 13β-substitution pattern and a new 6/8/6-ring taxane from Taxus cuspidata

Abstract

Keywords

ASJC Scopus subject areas

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