Study on site specific cleavage of RNA.

H. Shirakura; K. Hosono; G. Kawai; K. Takai; T. Ohtsuki; K. Watanabe; K. Sakamoto; S. Yokoyama; H. Takaku

Study on site specific cleavage of RNA.

H. Shirakura, K. Hosono, G. Kawai, K. Takai, T. Ohtsuki, K. Watanabe, K. Sakamoto, S. Yokoyama, H. Takaku

Research output: Contribution to journal › Article › peer-review

Abstract

The precursor of an RNA molecule from bacteriophage T4 infected Escherichia coli cell (p2Sp1 RNA) has the ability to cleave itself. It has been found that the site specific RNA cleavage reaction occurred at the pyridine-adenosine sequence in the presence of a monovalent cation and a non-ionic detergent. In order to investigate the mechanism of this cleavage reaction, we designed a RNA oligonucleotide (UUUAUU) and this RNA was cleavage activity at the U-A sequence.

Original language	English
Pages (from-to)	217-218
Number of pages	2
Journal	Nucleic acids symposium series
Issue number	37
Publication status	Published - 1997
Externally published	Yes

ASJC Scopus subject areas

Medicine(all)

Cite this

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title = "Study on site specific cleavage of RNA.",

abstract = "The precursor of an RNA molecule from bacteriophage T4 infected Escherichia coli cell (p2Sp1 RNA) has the ability to cleave itself. It has been found that the site specific RNA cleavage reaction occurred at the pyridine-adenosine sequence in the presence of a monovalent cation and a non-ionic detergent. In order to investigate the mechanism of this cleavage reaction, we designed a RNA oligonucleotide (UUUAUU) and this RNA was cleavage activity at the U-A sequence.",

author = "H. Shirakura and K. Hosono and G. Kawai and K. Takai and T. Ohtsuki and K. Watanabe and K. Sakamoto and S. Yokoyama and H. Takaku",

year = "1997",

language = "English",

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journal = "Nucleic acids symposium series",

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T1 - Study on site specific cleavage of RNA.

AU - Shirakura, H.

AU - Hosono, K.

AU - Kawai, G.

AU - Takai, K.

AU - Ohtsuki, T.

AU - Watanabe, K.

AU - Sakamoto, K.

AU - Yokoyama, S.

AU - Takaku, H.

PY - 1997

Y1 - 1997

N2 - The precursor of an RNA molecule from bacteriophage T4 infected Escherichia coli cell (p2Sp1 RNA) has the ability to cleave itself. It has been found that the site specific RNA cleavage reaction occurred at the pyridine-adenosine sequence in the presence of a monovalent cation and a non-ionic detergent. In order to investigate the mechanism of this cleavage reaction, we designed a RNA oligonucleotide (UUUAUU) and this RNA was cleavage activity at the U-A sequence.

AB - The precursor of an RNA molecule from bacteriophage T4 infected Escherichia coli cell (p2Sp1 RNA) has the ability to cleave itself. It has been found that the site specific RNA cleavage reaction occurred at the pyridine-adenosine sequence in the presence of a monovalent cation and a non-ionic detergent. In order to investigate the mechanism of this cleavage reaction, we designed a RNA oligonucleotide (UUUAUU) and this RNA was cleavage activity at the U-A sequence.

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M3 - Article

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SN - 0261-3166

SP - 217

EP - 218

JO - Nucleic acids symposium series

JF - Nucleic acids symposium series

IS - 37

ER -

Study on site specific cleavage of RNA.

Abstract

ASJC Scopus subject areas

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