Study on the metabolites of isoalantolactone in vivo and in vitro by ultra performance liquid chromatography combined with Triple TOF mass spectrometry

Agriculture & Biology

• ultra-performance liquid chromatography 64%
• mass spectrometry 42%
• metabolites 33%
• metabolism 29%
• sulfur 28%
• condiments 22%
• acetylcysteine 21%
• hydrogenation 21%
• demethylation 19%
• sesquiterpenoids 16%
• intestinal microorganisms 16%
• biotransformation 16%
• tandem mass spectrometry 15%
• medicinal plants 14%
• cysteine 14%
• vegetables 13%
• oxidation 12%
• rats 8%

Medicine & Life Sciences

• isoalantolactone 100%
• Liquid Chromatography 52%
• Mass Spectrometry 45%
• In Vitro Techniques 22%
• Sulfur 19%
• Hydrogenation 13%
• Condiments 13%
• Sesquiterpenes 11%
• Demethylation 10%
• Biotransformation 9%
• Acetylcysteine 9%
• Medicinal Plants 9%
• Vegetables 8%
• Cysteine 7%
• Bacteria 5%
• Safety 4%

Chemical Compounds

• Isoalantolactone 91%
• Ultra Performance Liquid Chromatography 62%
• Metabolite 35%
• Mass Spectrometry 33%
• Pharmacological Metabolism 19%
• Metabolic Reaction 11%
• Demethylation 9%
• Sesquiterpene 9%
• Time-of-Flight Mass Spectrometry 8%
• Cysteine 7%
• Safety 7%
• Double Bond 6%
• Hydrogenation 6%
• Oxidation Reaction 3%