Successful treatment of sepsis caused by Staphylococcus lugdunensis in an adult with 22q11.2 deletion syndrome

Shoji Hirasaki; Kazutoshi Murakami; Takaaki Mizushima; Kazuyoshi Ohmori; Seiko Fujita; Yoshihisa Hanayama; Tatsuya Kanamori; Ryo Yokota; Hirotaka Ebara; Nobuchika Kusano; Chieko Kudo; Tomoko Yamaguchi; Teiji Akagi; Norio Koide

doi:10.2169/internalmedicine.51.6257

Successful treatment of sepsis caused by Staphylococcus lugdunensis in an adult with 22q11.2 deletion syndrome

Shoji Hirasaki, Kazutoshi Murakami, Takaaki Mizushima, Kazuyoshi Ohmori, Seiko Fujita, Yoshihisa Hanayama, Tatsuya Kanamori, Ryo Yokota, Hirotaka Ebara, Nobuchika Kusano, Chieko Kudo, Tomoko Yamaguchi, Teiji Akagi, Norio Koide

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4 Citations (Scopus)

Abstract

A 27-year-old woman visited our hospital because of high fever. She had been diagnosed as 22q11.2 deletion syndrome (22q11.2DS) due to her cardiac history (tetralogy of Fallot), thymic hypoplasia and 22q11.2 deletion. She had a normal CD4/CD8 ratio, a slightly decreased lymphocyte count and normal serum immunoglobulin levels. Blood cultures were positive for Staphylococcus lugdunensis (S. lugdunensis). Infection route of S. lugdunensis in this case was unclear. The patient was successfully treated with several intravenous antibiotics. Infection should be considered when managing patients with 22q.11.2DS. regardless of whether their immune system is impaired.

Original language	English
Pages (from-to)	377-380
Number of pages	4
Journal	Internal Medicine
Volume	51
Issue number	4
DOIs	https://doi.org/10.2169/internalmedicine.51.6257
Publication status	Published - 2012

Keywords

Blood culture
Dental disease
Staphylococcal infection
Tetralogy of fallot

ASJC Scopus subject areas

Internal Medicine

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10.2169/internalmedicine.51.6257

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Hirasaki, S., Murakami, K., Mizushima, T., Ohmori, K., Fujita, S., Hanayama, Y., Kanamori, T., Yokota, R., Ebara, H., Kusano, N., Kudo, C., Yamaguchi, T., Akagi, T., & Koide, N. (2012). Successful treatment of sepsis caused by Staphylococcus lugdunensis in an adult with 22q11.2 deletion syndrome. Internal Medicine, 51(4), 377-380. https://doi.org/10.2169/internalmedicine.51.6257

Hirasaki, S, Murakami, K, Mizushima, T, Ohmori, K, Fujita, S, Hanayama, Y, Kanamori, T, Yokota, R, Ebara, H, Kusano, N, Kudo, C, Yamaguchi, T, Akagi, T & Koide, N 2012, 'Successful treatment of sepsis caused by Staphylococcus lugdunensis in an adult with 22q11.2 deletion syndrome', Internal Medicine, vol. 51, no. 4, pp. 377-380. https://doi.org/10.2169/internalmedicine.51.6257

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title = "Successful treatment of sepsis caused by Staphylococcus lugdunensis in an adult with 22q11.2 deletion syndrome",

abstract = "A 27-year-old woman visited our hospital because of high fever. She had been diagnosed as 22q11.2 deletion syndrome (22q11.2DS) due to her cardiac history (tetralogy of Fallot), thymic hypoplasia and 22q11.2 deletion. She had a normal CD4/CD8 ratio, a slightly decreased lymphocyte count and normal serum immunoglobulin levels. Blood cultures were positive for Staphylococcus lugdunensis (S. lugdunensis). Infection route of S. lugdunensis in this case was unclear. The patient was successfully treated with several intravenous antibiotics. Infection should be considered when managing patients with 22q.11.2DS. regardless of whether their immune system is impaired.",

keywords = "Blood culture, Dental disease, Staphylococcal infection, Tetralogy of fallot",

author = "Shoji Hirasaki and Kazutoshi Murakami and Takaaki Mizushima and Kazuyoshi Ohmori and Seiko Fujita and Yoshihisa Hanayama and Tatsuya Kanamori and Ryo Yokota and Hirotaka Ebara and Nobuchika Kusano and Chieko Kudo and Tomoko Yamaguchi and Teiji Akagi and Norio Koide",

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AU - Hirasaki, Shoji

AU - Murakami, Kazutoshi

AU - Mizushima, Takaaki

AU - Ohmori, Kazuyoshi

AU - Fujita, Seiko

AU - Hanayama, Yoshihisa

AU - Kanamori, Tatsuya

AU - Yokota, Ryo

AU - Ebara, Hirotaka

AU - Kusano, Nobuchika

AU - Kudo, Chieko

AU - Yamaguchi, Tomoko

AU - Akagi, Teiji

AU - Koide, Norio

PY - 2012

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AB - A 27-year-old woman visited our hospital because of high fever. She had been diagnosed as 22q11.2 deletion syndrome (22q11.2DS) due to her cardiac history (tetralogy of Fallot), thymic hypoplasia and 22q11.2 deletion. She had a normal CD4/CD8 ratio, a slightly decreased lymphocyte count and normal serum immunoglobulin levels. Blood cultures were positive for Staphylococcus lugdunensis (S. lugdunensis). Infection route of S. lugdunensis in this case was unclear. The patient was successfully treated with several intravenous antibiotics. Infection should be considered when managing patients with 22q.11.2DS. regardless of whether their immune system is impaired.

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KW - Dental disease

KW - Staphylococcal infection

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Successful treatment of sepsis caused by Staphylococcus lugdunensis in an adult with 22q11.2 deletion syndrome

Abstract

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