TY - JOUR
T1 - Surgical treatment of submacular hemorrhage associated with idiopathic polypoidal choroidal vasculopathy
AU - Shiraga, Fumio
AU - Matsuo, Toshihiko
AU - Yokoe, Shiho
AU - Takasu, Ippei
AU - Okanouchi, Toshio
AU - Ohtsuki, Hiroshi
AU - Grossniklaus, Hans E.
N1 - Funding Information:
This study was supported in part by the Health Sciences Research Grants from the Ministry of Health and Welfare, Tokyo, Japan.
PY - 1999/8
Y1 - 1999/8
N2 - PURPOSE: To report the visual outcome of surgical treatment of submacular hemorrhage associated with idiopathic polypoidal choroidal vasculopathy. METHODS: Eight eyes of eight consecutive patients with thick submacular hemorrhages associated with idiopathic polypoidal choroidal vasculopathy were treated with pars plana vitrectomy and tissue plasminogen activator-assisted removal of subretinal blood (December 1995 to September 1997) or intravitreal 100% sulfur hexafluoride gas injection without tissue plasminogen activator (October 1997 to March 1998). RESULTS: Postoperatively, laser treatment was performed for active polypoidal lesions outside the foveal avascular zone in four eyes. A retinal pigment epithelial tear was seen outside the foveal avascular zone in three eyes, and one eye developed a retinal detachment. The best-corrected visual acuity improved (by 3 or more lines) or stabilized in seven of the eight eyes. Four eyes had a final best- corrected visual acuity of 20/40 or better, and three eyes had a final best- corrected visual acuity of 20/50 to 20/200. In one eye, the visual acuity decreased from 20/100 to 20/500 because of the development of a subfoveal neovascular membrane. The membrane was excised, and histologic examination showed fibrovascular tissue between the retina and retinal pigment epithelium (type 2 pattern). CONCLUSIONS: Surgical intervention may be of benefit in eyes with submacular hemorrhage associated with idiopathic polypoidal choroidal vasculopathy.
AB - PURPOSE: To report the visual outcome of surgical treatment of submacular hemorrhage associated with idiopathic polypoidal choroidal vasculopathy. METHODS: Eight eyes of eight consecutive patients with thick submacular hemorrhages associated with idiopathic polypoidal choroidal vasculopathy were treated with pars plana vitrectomy and tissue plasminogen activator-assisted removal of subretinal blood (December 1995 to September 1997) or intravitreal 100% sulfur hexafluoride gas injection without tissue plasminogen activator (October 1997 to March 1998). RESULTS: Postoperatively, laser treatment was performed for active polypoidal lesions outside the foveal avascular zone in four eyes. A retinal pigment epithelial tear was seen outside the foveal avascular zone in three eyes, and one eye developed a retinal detachment. The best-corrected visual acuity improved (by 3 or more lines) or stabilized in seven of the eight eyes. Four eyes had a final best- corrected visual acuity of 20/40 or better, and three eyes had a final best- corrected visual acuity of 20/50 to 20/200. In one eye, the visual acuity decreased from 20/100 to 20/500 because of the development of a subfoveal neovascular membrane. The membrane was excised, and histologic examination showed fibrovascular tissue between the retina and retinal pigment epithelium (type 2 pattern). CONCLUSIONS: Surgical intervention may be of benefit in eyes with submacular hemorrhage associated with idiopathic polypoidal choroidal vasculopathy.
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U2 - 10.1016/S0002-9394(99)00078-1
DO - 10.1016/S0002-9394(99)00078-1
M3 - Article
C2 - 10458169
AN - SCOPUS:0032797726
SN - 0002-9394
VL - 128
SP - 147
EP - 154
JO - American Journal of Ophthalmology
JF - American Journal of Ophthalmology
IS - 2
ER -