TY - JOUR
T1 - Survival of patients treated by an autonomic nerve-preserving gastrectomy for early gastric cancer
AU - Sasada, Shinsuke
AU - Ninomiya, Motoki
AU - Nishizaki, Masahiko
AU - Harano, Masao
AU - Ojima, Yasutomo
AU - Matsukawa, Hiroyoshi
AU - Shiozaki, Shigehiro
AU - Ohno, Satoshi
AU - Takakura, Norihisa
PY - 2010/5/1
Y1 - 2010/5/1
N2 - Purpose. Autonomic nerve preservation in a gastrectomy for gastric cancer improves the postoperative quality of life. We retrospectively examined the survival of patients treated by an autonomic nerve-preserving gastrectomy in comparison to the survival of the patients treated by a conventional gastrectomy. Methods. The survival of 385 patients treated by an autonomic nerve-preserving gastrectomy for clinical early gastric cancer (the ANP group) was compared with that of 285 patients treated by a conventional gastrectomy (non-ANP group). Results. Among the ANP group, the numbers of patients with tumor invasion to the mucosa, submucosa, and muscularis propria were 210, 166, and 9, respectively, whereas the numbers of patients with lymph node metastasis grades of N0, N1, and N2 were 360, 21, and 4, respectively. The overall 5-year survival rate of the ANP group was 94.7%, which was superior to that of the non-ANP group (90.4%; P = 0.003). The 5-year survival rates of patients with lymph node metastasis were 94.9% and 91.8% in the ANP and non-ANP groups, respectively (P = 0.733). Only 3 patients in the ANP group died from gastric cancer. Conclusions. The survival of patients treated by an autonomic nerve-preserving gastrectomy was equivalent to that of patients treated by a conventional gastrectomy, thus suggesting that an autonomic nervepreserving gastrectomy could be a useful procedure for the treatment of early gastric cancer.
AB - Purpose. Autonomic nerve preservation in a gastrectomy for gastric cancer improves the postoperative quality of life. We retrospectively examined the survival of patients treated by an autonomic nerve-preserving gastrectomy in comparison to the survival of the patients treated by a conventional gastrectomy. Methods. The survival of 385 patients treated by an autonomic nerve-preserving gastrectomy for clinical early gastric cancer (the ANP group) was compared with that of 285 patients treated by a conventional gastrectomy (non-ANP group). Results. Among the ANP group, the numbers of patients with tumor invasion to the mucosa, submucosa, and muscularis propria were 210, 166, and 9, respectively, whereas the numbers of patients with lymph node metastasis grades of N0, N1, and N2 were 360, 21, and 4, respectively. The overall 5-year survival rate of the ANP group was 94.7%, which was superior to that of the non-ANP group (90.4%; P = 0.003). The 5-year survival rates of patients with lymph node metastasis were 94.9% and 91.8% in the ANP and non-ANP groups, respectively (P = 0.733). Only 3 patients in the ANP group died from gastric cancer. Conclusions. The survival of patients treated by an autonomic nerve-preserving gastrectomy was equivalent to that of patients treated by a conventional gastrectomy, thus suggesting that an autonomic nervepreserving gastrectomy could be a useful procedure for the treatment of early gastric cancer.
KW - Autonomic nerve preservation
KW - Gastrectomy
KW - Gastric cancer
KW - Survival
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U2 - 10.1007/s00595-009-4067-9
DO - 10.1007/s00595-009-4067-9
M3 - Article
C2 - 20425548
AN - SCOPUS:77955687860
SN - 0941-1291
VL - 40
SP - 444
EP - 450
JO - Japanese Journal of Surgery
JF - Japanese Journal of Surgery
IS - 5
ER -
