Synthesis of a luminescent compound: 8-dimethylaminopyridazino[4,5-a][2.2.3]cyclazine-1,4(2H,3H)-diones

Yoshinori Tominaga, Kaori Komiya, Seigo Kataoka, Yasuhiro Shigemitsu, Takashi Hirota, Kenji Sasaki

    Research output: Contribution to journalArticlepeer-review

    13 Citations (Scopus)


    Some pyridazino[4,5-a][2.2.3]cyclazine-1,4(2H,3H)-diones (1a-d) as a luminescent compound were synthesized via several steps from indolizine derivatives. The key intermediates, dimethyl 6-dimethylamino[2.2.3]cyclazine-1,2-dicarboxylates (5, 7) were synthesized by the [8 + 2] cycloaddition reaction of 7-dimethylaminoindolizines (4, 6) with dimethyl acetylenedicarboxylate in the presence of Pd-C in refluxing toluene.

    Original languageEnglish
    Pages (from-to)1985-1988
    Number of pages4
    Issue number10
    Publication statusPublished - Jan 1 1998

    ASJC Scopus subject areas

    • Analytical Chemistry
    • Pharmacology
    • Organic Chemistry


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