Synthesis of bioactive organic-inorganic hybrids with γ-methacryloxypropyltrimethoxysilane

Takeshi Yabuta; Kanji Tsuru; Satoshi Hayakawa; Chikara Ohtsuki; Akiyoshi Osaka

doi:10.1023/A:1008795629804

Synthesis of bioactive organic-inorganic hybrids with γ-methacryloxypropyltrimethoxysilane

Takeshi Yabuta, Kanji Tsuru, Satoshi Hayakawa, Chikara Ohtsuki, Akiyoshi Osaka

Research output: Contribution to journal › Conference article › peer-review

27 Citations (Scopus)

Abstract

Bioactive organic-inorganic hybrids were synthesized through sol-gel processing starting from γ-methacryloxypropyltrimethoxysilane. NMR-spectroscopic studies showed the presence of silanol groups (Si-OH) and Si-O-Si bonds. In vitro tests of the hybrids for bioactivity with a simulated body fluid (Kokubo solution) indicated that only calcium-containing hybrids could form apatite on their surfaces. Thus the presence of calcium ions was no less important to deposit apatite than the formation of silanol groups or Si-O-Si bonds.

Original language	English
Pages (from-to)	745-748
Number of pages	4
Journal	Journal of Sol-Gel Science and Technology
Volume	19
Issue number	1-3
DOIs	https://doi.org/10.1023/A:1008795629804
Publication status	Published - Dec 2000
Event	10th International Workshop pn Glass and Ceramics, Hybrids and Nanocomposites from Gels - Yokohama, Jpn Duration: Sept 20 1999 → Sept 24 1999

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Ceramics and Composites
General Chemistry
Biomaterials
Condensed Matter Physics
Materials Chemistry

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title = "Synthesis of bioactive organic-inorganic hybrids with γ-methacryloxypropyltrimethoxysilane",

abstract = "Bioactive organic-inorganic hybrids were synthesized through sol-gel processing starting from γ-methacryloxypropyltrimethoxysilane. NMR-spectroscopic studies showed the presence of silanol groups (Si-OH) and Si-O-Si bonds. In vitro tests of the hybrids for bioactivity with a simulated body fluid (Kokubo solution) indicated that only calcium-containing hybrids could form apatite on their surfaces. Thus the presence of calcium ions was no less important to deposit apatite than the formation of silanol groups or Si-O-Si bonds.",

author = "Takeshi Yabuta and Kanji Tsuru and Satoshi Hayakawa and Chikara Ohtsuki and Akiyoshi Osaka",

note = "Funding Information: Financial support by a grant from The Japan Securities Scholarship Foundation is gratefully acknowledged. We are grateful to the SS-NMR Division of the VB Laboratory of Okayama University for the 13C and 29Si MAS NMR experiments.; 10th International Workshop pn Glass and Ceramics, Hybrids and Nanocomposites from Gels ; Conference date: 20-09-1999 Through 24-09-1999",

year = "2000",

month = dec,

doi = "10.1023/A:1008795629804",

language = "English",

volume = "19",

pages = "745--748",

journal = "Journal of Sol-Gel Science and Technology",

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T1 - Synthesis of bioactive organic-inorganic hybrids with γ-methacryloxypropyltrimethoxysilane

AU - Yabuta, Takeshi

AU - Tsuru, Kanji

AU - Hayakawa, Satoshi

AU - Ohtsuki, Chikara

AU - Osaka, Akiyoshi

N1 - Funding Information: Financial support by a grant from The Japan Securities Scholarship Foundation is gratefully acknowledged. We are grateful to the SS-NMR Division of the VB Laboratory of Okayama University for the 13C and 29Si MAS NMR experiments.

PY - 2000/12

Y1 - 2000/12

N2 - Bioactive organic-inorganic hybrids were synthesized through sol-gel processing starting from γ-methacryloxypropyltrimethoxysilane. NMR-spectroscopic studies showed the presence of silanol groups (Si-OH) and Si-O-Si bonds. In vitro tests of the hybrids for bioactivity with a simulated body fluid (Kokubo solution) indicated that only calcium-containing hybrids could form apatite on their surfaces. Thus the presence of calcium ions was no less important to deposit apatite than the formation of silanol groups or Si-O-Si bonds.

AB - Bioactive organic-inorganic hybrids were synthesized through sol-gel processing starting from γ-methacryloxypropyltrimethoxysilane. NMR-spectroscopic studies showed the presence of silanol groups (Si-OH) and Si-O-Si bonds. In vitro tests of the hybrids for bioactivity with a simulated body fluid (Kokubo solution) indicated that only calcium-containing hybrids could form apatite on their surfaces. Thus the presence of calcium ions was no less important to deposit apatite than the formation of silanol groups or Si-O-Si bonds.

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DO - 10.1023/A:1008795629804

M3 - Conference article

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JO - Journal of Sol-Gel Science and Technology

JF - Journal of Sol-Gel Science and Technology

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Y2 - 20 September 1999 through 24 September 1999

ER -

Synthesis of bioactive organic-inorganic hybrids with γ-methacryloxypropyltrimethoxysilane

Abstract

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