Synthesis of highly oxygenated biphenyl derivative in an optically active form through palladium-mediated intramolecular biaryl coupling reaction

Hitoshi Abe; Masatsugu Arai; Keisuke Nishioka; Tatsuya Kida; Kazuma Shioe; Yasuo Takeuchi; Takashi Harayama

doi:10.3987/COM-08-S(N)8

Synthesis of highly oxygenated biphenyl derivative in an optically active form through palladium-mediated intramolecular biaryl coupling reaction

Hitoshi Abe, Masatsugu Arai, Keisuke Nishioka, Tatsuya Kida, Kazuma Shioe, Yasuo Takeuchi, Takashi Harayama

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Optically active 6,6'-dihydroxymethyl-2,2'-3,3'-4,4'-hexamethoxybiphenyl (1) was prepared via the Pd-mediated biaryl coupling reaction of a phenyl benzoate derivative and the following enantioselective lactone opening reaction.

Original language	English
Pages (from-to)	291-303
Number of pages	13
Journal	Heterocycles
Volume	76
Issue number	1
DOIs	https://doi.org/10.3987/COM-08-S(N)8
Publication status	Published - 2008

ASJC Scopus subject areas

Analytical Chemistry
Pharmacology
Organic Chemistry

Access to Document

10.3987/COM-08-S(N)8

Cite this

@article{e6a06279dd9548d8b66ea671ea8d0a48,

title = "Synthesis of highly oxygenated biphenyl derivative in an optically active form through palladium-mediated intramolecular biaryl coupling reaction",

abstract = "Optically active 6,6'-dihydroxymethyl-2,2'-3,3'-4,4'-hexamethoxybiphenyl (1) was prepared via the Pd-mediated biaryl coupling reaction of a phenyl benzoate derivative and the following enantioselective lactone opening reaction.",

author = "Hitoshi Abe and Masatsugu Arai and Keisuke Nishioka and Tatsuya Kida and Kazuma Shioe and Yasuo Takeuchi and Takashi Harayama",

year = "2008",

doi = "10.3987/COM-08-S(N)8",

language = "English",

volume = "76",

pages = "291--303",

journal = "Heterocycles",

issn = "0385-5414",

publisher = "Japan Institute of Heterocyclic Chemistry",

number = "1",

}

TY - JOUR

T1 - Synthesis of highly oxygenated biphenyl derivative in an optically active form through palladium-mediated intramolecular biaryl coupling reaction

AU - Abe, Hitoshi

AU - Arai, Masatsugu

AU - Nishioka, Keisuke

AU - Kida, Tatsuya

AU - Shioe, Kazuma

AU - Takeuchi, Yasuo

AU - Harayama, Takashi

PY - 2008

Y1 - 2008

N2 - Optically active 6,6'-dihydroxymethyl-2,2'-3,3'-4,4'-hexamethoxybiphenyl (1) was prepared via the Pd-mediated biaryl coupling reaction of a phenyl benzoate derivative and the following enantioselective lactone opening reaction.

AB - Optically active 6,6'-dihydroxymethyl-2,2'-3,3'-4,4'-hexamethoxybiphenyl (1) was prepared via the Pd-mediated biaryl coupling reaction of a phenyl benzoate derivative and the following enantioselective lactone opening reaction.

UR - http://www.scopus.com/inward/record.url?scp=77955676901&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=77955676901&partnerID=8YFLogxK

U2 - 10.3987/COM-08-S(N)8

DO - 10.3987/COM-08-S(N)8

M3 - Article

AN - SCOPUS:77955676901

SN - 0385-5414

VL - 76

SP - 291

EP - 303

JO - Heterocycles

JF - Heterocycles

IS - 1

ER -

Synthesis of highly oxygenated biphenyl derivative in an optically active form through palladium-mediated intramolecular biaryl coupling reaction

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this