Synthesis of N1-and N8-(γ-L-Glutamyl) spermidines and (γ-L-Glutamyl) putrescine

Kazuya Toho; Naoki Abe; Teiko Yamada; Yoshifumi Ito; Hiroyuki Konno; Shigefumi Kuwahara; Hiromasa Kiyota

doi:10.2174/157017811794557813

Synthesis of N¹-and N⁸-(γ-L-Glutamyl) spermidines and (γ-L-Glutamyl) putrescine

Kazuya Toho, Naoki Abe, Teiko Yamada, Yoshifumi Ito, Hiroyuki Konno, Shigefumi Kuwahara, Hiromasa Kiyota

Research output: Contribution to journal › Article › peer-review

Abstract

(γ-L-Glutamyl)putrescine and N¹- and N⁸- (γ-L-glutamyl)spermidines, possible regioisomeric products of the polyamine glutamyl transferase of bacteria such as Escherichia coli and Pseudomonas aeruginosa, were synthesized from N-Boc-protected putrescine and 1,3-propanediamine.

Original language	English
Pages (from-to)	1-4
Number of pages	4
Journal	Letters in Organic Chemistry
Volume	8
Issue number	1
DOIs	https://doi.org/10.2174/157017811794557813
Publication status	Published - Jan 2011
Externally published	Yes

Keywords

Glutamylputrescine
Glutamylspermidine
Polyamine biosynthesis
Polyamine glutamyl transferase
Pseudomonas aeruginosa

ASJC Scopus subject areas

Biochemistry
Organic Chemistry

Access to Document

10.2174/157017811794557813

Cite this

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title = "Synthesis of N1-and N8-(γ-L-Glutamyl) spermidines and (γ-L-Glutamyl) putrescine",

abstract = "(γ-L-Glutamyl)putrescine and N1- and N8- (γ-L-glutamyl)spermidines, possible regioisomeric products of the polyamine glutamyl transferase of bacteria such as Escherichia coli and Pseudomonas aeruginosa, were synthesized from N-Boc-protected putrescine and 1,3-propanediamine.",

keywords = "Glutamylputrescine, Glutamylspermidine, Polyamine biosynthesis, Polyamine glutamyl transferase, Pseudomonas aeruginosa",

author = "Kazuya Toho and Naoki Abe and Teiko Yamada and Yoshifumi Ito and Hiroyuki Konno and Shigefumi Kuwahara and Hiromasa Kiyota",

year = "2011",

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T1 - Synthesis of N1-and N8-(γ-L-Glutamyl) spermidines and (γ-L-Glutamyl) putrescine

AU - Toho, Kazuya

AU - Abe, Naoki

AU - Yamada, Teiko

AU - Ito, Yoshifumi

AU - Konno, Hiroyuki

AU - Kuwahara, Shigefumi

AU - Kiyota, Hiromasa

PY - 2011/1

Y1 - 2011/1

N2 - (γ-L-Glutamyl)putrescine and N1- and N8- (γ-L-glutamyl)spermidines, possible regioisomeric products of the polyamine glutamyl transferase of bacteria such as Escherichia coli and Pseudomonas aeruginosa, were synthesized from N-Boc-protected putrescine and 1,3-propanediamine.

AB - (γ-L-Glutamyl)putrescine and N1- and N8- (γ-L-glutamyl)spermidines, possible regioisomeric products of the polyamine glutamyl transferase of bacteria such as Escherichia coli and Pseudomonas aeruginosa, were synthesized from N-Boc-protected putrescine and 1,3-propanediamine.

KW - Glutamylputrescine

KW - Glutamylspermidine

KW - Polyamine biosynthesis

KW - Polyamine glutamyl transferase

KW - Pseudomonas aeruginosa

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