Synthesis of PDMS-based porous materials for biomedical applications

T. Yabuta; E. P. Bescher; J. D. Mackenzie; K. Tsuru; S. Hayakawa; A. Osaka

doi:10.1023/A:1020772521781

Synthesis of PDMS-based porous materials for biomedical applications

T. Yabuta, E. P. Bescher, J. D. Mackenzie, K. Tsuru, S. Hayakawa, A. Osaka

Research output: Contribution to journal › Article › peer-review

58 Citations (Scopus)

Abstract

Polydimethylsiloxane (PDMS) and tetraethoxysilane (TEOS)-based porous organically modified silicates (ORMOSILs) for biomedical applications were synthesized through a sol-gel process, using sucrose particles as templates. These materials were characterized by ²⁹Si CP-MAS NMR spectroscopy, thin film X-ray diffraction, and scanning electron microscopy. Their bioactivity was evaluated using a simulated body fluid (SBF) of Kokubo recipe. These materials had a bimodal porous structure with pores of 300-500 μm and 10-50 μm in diameter. NMR showed that the silanol groups of the PDMS chain cross-linked to silica derived from the hydrolysis and condensation of TEOS. The samples containing Ca(II) exhibited apatite deposition on the pore walls within 3 days in SBF.

Original language	English
Pages (from-to)	1219-1222
Number of pages	4
Journal	Journal of Sol-Gel Science and Technology
Volume	26
Issue number	1-3
DOIs	https://doi.org/10.1023/A:1020772521781
Publication status	Published - Jan 2003

Keywords

Apatite deposition
Bioactivity
Ormosil
Porous hybrid
Simulated body fluid

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Ceramics and Composites
Chemistry(all)
Biomaterials
Condensed Matter Physics
Materials Chemistry

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title = "Synthesis of PDMS-based porous materials for biomedical applications",

abstract = "Polydimethylsiloxane (PDMS) and tetraethoxysilane (TEOS)-based porous organically modified silicates (ORMOSILs) for biomedical applications were synthesized through a sol-gel process, using sucrose particles as templates. These materials were characterized by 29Si CP-MAS NMR spectroscopy, thin film X-ray diffraction, and scanning electron microscopy. Their bioactivity was evaluated using a simulated body fluid (SBF) of Kokubo recipe. These materials had a bimodal porous structure with pores of 300-500 μm and 10-50 μm in diameter. NMR showed that the silanol groups of the PDMS chain cross-linked to silica derived from the hydrolysis and condensation of TEOS. The samples containing Ca(II) exhibited apatite deposition on the pore walls within 3 days in SBF.",

keywords = "Apatite deposition, Bioactivity, Ormosil, Porous hybrid, Simulated body fluid",

author = "T. Yabuta and Bescher, {E. P.} and Mackenzie, {J. D.} and K. Tsuru and S. Hayakawa and A. Osaka",

note = "Funding Information: This work was financially supported by the Grant-in-Aid for Scientific Research (B) (2) (11694162), the Ministry of Education, Culture, Sports, Science & Technology, Japan. We are grateful to the SS-NMR Division of the VB Laboratory of Okayama University for the 29Si CP-MAS NMR experiments.",

year = "2003",

month = jan,

doi = "10.1023/A:1020772521781",

language = "English",

volume = "26",

pages = "1219--1222",

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T1 - Synthesis of PDMS-based porous materials for biomedical applications

AU - Yabuta, T.

AU - Bescher, E. P.

AU - Mackenzie, J. D.

AU - Tsuru, K.

AU - Hayakawa, S.

AU - Osaka, A.

N1 - Funding Information: This work was financially supported by the Grant-in-Aid for Scientific Research (B) (2) (11694162), the Ministry of Education, Culture, Sports, Science & Technology, Japan. We are grateful to the SS-NMR Division of the VB Laboratory of Okayama University for the 29Si CP-MAS NMR experiments.

PY - 2003/1

Y1 - 2003/1

N2 - Polydimethylsiloxane (PDMS) and tetraethoxysilane (TEOS)-based porous organically modified silicates (ORMOSILs) for biomedical applications were synthesized through a sol-gel process, using sucrose particles as templates. These materials were characterized by 29Si CP-MAS NMR spectroscopy, thin film X-ray diffraction, and scanning electron microscopy. Their bioactivity was evaluated using a simulated body fluid (SBF) of Kokubo recipe. These materials had a bimodal porous structure with pores of 300-500 μm and 10-50 μm in diameter. NMR showed that the silanol groups of the PDMS chain cross-linked to silica derived from the hydrolysis and condensation of TEOS. The samples containing Ca(II) exhibited apatite deposition on the pore walls within 3 days in SBF.

AB - Polydimethylsiloxane (PDMS) and tetraethoxysilane (TEOS)-based porous organically modified silicates (ORMOSILs) for biomedical applications were synthesized through a sol-gel process, using sucrose particles as templates. These materials were characterized by 29Si CP-MAS NMR spectroscopy, thin film X-ray diffraction, and scanning electron microscopy. Their bioactivity was evaluated using a simulated body fluid (SBF) of Kokubo recipe. These materials had a bimodal porous structure with pores of 300-500 μm and 10-50 μm in diameter. NMR showed that the silanol groups of the PDMS chain cross-linked to silica derived from the hydrolysis and condensation of TEOS. The samples containing Ca(II) exhibited apatite deposition on the pore walls within 3 days in SBF.

KW - Apatite deposition

KW - Bioactivity

KW - Ormosil

KW - Porous hybrid

KW - Simulated body fluid

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Synthesis of PDMS-based porous materials for biomedical applications

Abstract

Keywords

ASJC Scopus subject areas

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