Abstract
The synthesis of the southern (C1′-C11′) fragment of pamamycin-635A, isolated from Streptomyces alboniger, was achieved via an Evans aldol reaction, a cis-selective iodoetherification and a stereospecific deiodination as the key steps.
Original language | English |
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Pages (from-to) | 1061-1067 |
Number of pages | 7 |
Journal | Tetrahedron |
Volume | 61 |
Issue number | 5 |
DOIs | |
Publication status | Published - Jan 31 2005 |
Externally published | Yes |
Keywords
- Evans aldol reaction
- Iodoetherification
- Pamamycins
- Synthesis
ASJC Scopus subject areas
- Biochemistry
- Drug Discovery
- Organic Chemistry