Interferon-gamma inducing factor (IGIF) is a new cytokine which is thought to be useful clinically as an anti-tumor agent. Fas ligand (FasL) is a type II membrane protein belonging to the necrosis factor family, which induces apoptosis by binding to its counter receptor, Fas. In this paper, we report the effect of IGIF for the expression of Fas and FasL in human healthy peripheral blood lymphocytes (PBLs). IGIF up regulates the expression of Fas and FasL in PBLs.
|Number of pages||2|
|Publication status||Published - Jan 1 1997|
ASJC Scopus subject areas
- Cancer Research