TY - JOUR
T1 - The efficacy and safety of single-session endoscopic ultrasound-guided fine needle aspiration and endoscopic retrograde cholangiopancreatography for evaluation of pancreatic masses
AU - Noma, Yasuhiro
AU - Kawamoto, Hirofumi
AU - Kato, Hironari
AU - Iwamuro, Masaya
AU - Hirao, Ken
AU - Fujii, Masakuni
AU - Tsutsumi, Koichiro
AU - Horiguchi, Shigeru
AU - Yamamoto, Naoki
AU - Sakakihara, Ichiro
AU - Tomoda, Takeshi
AU - Matsumoto, Kazuyuki
AU - Okada, Hiroyuki
AU - Yamamoto, Kazuhide
PY - 2014/9
Y1 - 2014/9
N2 - Background/Aims: There have been limited studies evaluating single-session EUS-FNA and ERCP for evaluation of pancreatic masses. The aim of this study was to determine the safety of single-session EUS-FNA and ERCP, and to compare the diagnostic accuracies of cytodiagnosis by EUS-FNA, ERCP, and their combination. Methodology: A total of 100 patients with pancreatic masses were prospectively enrolled. All patients underwent single-session EUS-FNA and ERCP. The main outcome measurement was frequency of post-procedural complications. Another measurement was diagnostic accuracy of cytodiagnosis by EUS-FNA, ERCP, and their combination. Results:Procedure-related pancreatitis occurred in 10 patients, but all patients were conservatively managed. Cytodiagnosis by EUS-FNA was significantly superior to ERCP in accuracy. In patients with a pancreatic head mass, 3 cases of false negative EUS-FNA were positive on ERCP. The combination procedures improved accuracy compared with EUS-FNA alone. By contrast, in the subgroup of the pancreatic body or tail mass, the combination of EUS-FNA and ERCP did not improve cytodiagnosis compared to that with EUS-FNA alone.Conclusions: Single-session EUS-FNA and ERCP appears to be as safe as performing each procedure separately. EUS-FNA should be considered the principal procedure for cytodiagnosis. ERCP has only a complementary role in patients with pancreatic head mass.
AB - Background/Aims: There have been limited studies evaluating single-session EUS-FNA and ERCP for evaluation of pancreatic masses. The aim of this study was to determine the safety of single-session EUS-FNA and ERCP, and to compare the diagnostic accuracies of cytodiagnosis by EUS-FNA, ERCP, and their combination. Methodology: A total of 100 patients with pancreatic masses were prospectively enrolled. All patients underwent single-session EUS-FNA and ERCP. The main outcome measurement was frequency of post-procedural complications. Another measurement was diagnostic accuracy of cytodiagnosis by EUS-FNA, ERCP, and their combination. Results:Procedure-related pancreatitis occurred in 10 patients, but all patients were conservatively managed. Cytodiagnosis by EUS-FNA was significantly superior to ERCP in accuracy. In patients with a pancreatic head mass, 3 cases of false negative EUS-FNA were positive on ERCP. The combination procedures improved accuracy compared with EUS-FNA alone. By contrast, in the subgroup of the pancreatic body or tail mass, the combination of EUS-FNA and ERCP did not improve cytodiagnosis compared to that with EUS-FNA alone.Conclusions: Single-session EUS-FNA and ERCP appears to be as safe as performing each procedure separately. EUS-FNA should be considered the principal procedure for cytodiagnosis. ERCP has only a complementary role in patients with pancreatic head mass.
KW - Endoscopic retrograde cholangiopancreatography
KW - Endoscopic ultrasound-guided fine needle aspiration
KW - Endosonography
KW - Pancreatic neoplasms
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U2 - 10.5754/hge13523
DO - 10.5754/hge13523
M3 - Article
C2 - 25436378
AN - SCOPUS:84906959584
SN - 0172-6390
VL - 61
SP - 1775
EP - 1779
JO - Acta hepato-splenologica
JF - Acta hepato-splenologica
IS - 134
ER -