Selective bromination of sucrose, followed by acetalation with 2,2-dimethoxypropane in 1,4-dioxane in the presence of p-toluenesulfonic acid, afforded methyl 6-bromo-6-deoxy-1,3-O-isopropylidene-α-d-fructofuranoside (4). The first chemical synthesis of 6-thio-d-fructopyranose was accomplished from 4 through its 6-S-acetyl-6-thio derivative.
|Number of pages||6|
|Publication status||Published - Mar 1 2007|
ASJC Scopus subject areas
- Analytical Chemistry
- Organic Chemistry