TY - JOUR
T1 - The function of rac small GTPase and associated proteins in rice innate immunity
AU - Kawano, Yoji
AU - Chen, Letian
AU - Shimamoto, Ko
N1 - Funding Information:
Acknowledgement This research was supported by Grants-in-Aid from the Ministry of Agriculture, Forestry, and Fisheries of Japan (Genomics for Agricultural Innovation, PMI-0007) and the Japan Society for the Promotion of Science (13G0023) to K.S. and the Naito Foundation and Maekawa Houonkai Foundation to Y.K.
PY - 2010/9
Y1 - 2010/9
N2 - Two types of innate immune receptors, pattern recognition receptors, and resistance proteins, play crucial roles in plant innate immunity; however, the molecules activated by the receptors and how immune responses are transmitted are not well understood. Evidence has been accumulating for a decade that Rac, a small guanosine triphosphatase (GTPase; also known as Rop) belonging to the Rho-type small GTPase family, is a key regulator of innate immunity in rice, barley, and other species. Like other small GTPases, Rac GTPases function as molecular switches by cycling between GDP-bound inactive and GTP-bound active forms in cells. Rac GTPase acts as a key signaling switch downstream of the two types of immune receptors and triggers innate immunity. This review outlines the role of the Rac family small GTPase and its associated proteins in rice innate immunity.
AB - Two types of innate immune receptors, pattern recognition receptors, and resistance proteins, play crucial roles in plant innate immunity; however, the molecules activated by the receptors and how immune responses are transmitted are not well understood. Evidence has been accumulating for a decade that Rac, a small guanosine triphosphatase (GTPase; also known as Rop) belonging to the Rho-type small GTPase family, is a key regulator of innate immunity in rice, barley, and other species. Like other small GTPases, Rac GTPases function as molecular switches by cycling between GDP-bound inactive and GTP-bound active forms in cells. Rac GTPase acts as a key signaling switch downstream of the two types of immune receptors and triggers innate immunity. This review outlines the role of the Rac family small GTPase and its associated proteins in rice innate immunity.
KW - G protein
KW - Plant immunity
KW - Rice
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U2 - 10.1007/s12284-010-9049-4
DO - 10.1007/s12284-010-9049-4
M3 - Review article
AN - SCOPUS:84856599955
SN - 1939-8425
VL - 3
SP - 112
EP - 121
JO - Rice
JF - Rice
IS - 2-3
ER -