TY - JOUR
T1 - The incidence of desaturation during anesthesia in adult and pediatric patients
T2 - A retrospective study
AU - Lemoto, Vika Fatafehi Hala ufia
AU - Sugimoto, Kentaro
AU - Kanazawa, Tomoyuki
AU - Matsuzaki, Takashi
AU - Morimatsu, Hiroshi
N1 - Funding Information:
We thank Dr. Robert J. McDougall, The Royal Children's Hospital, Melbourne, Australia for the helpful comments with the manuscript; Dr. Rhys Thomas, John Hunter Hospital, Newcastle, Australia for providing English editing; Dr. Toshiharu Mitsuhashi, Centre for Innovative Clinical Medicine, Okayama University, Okayama, Japan for helpful epidemiological feedback; and Mr. Sou Goken, Nihon-Kohden Okayama City, Japan for helping with the data extraction. This study's data were presented in part at the World Federation of Societies of Anaesthesiologists 16th World Congress of Anaesthesiologists, Hong Kong, August-September 2016.
PY - 2018
Y1 - 2018
N2 - We investigated the incidence of desaturation during general anesthesia in preoperatively hypoxic ( < 92%), and nonhypoxic (≥ 92%) pediatric (n=1,090) and adult (n=5,138) patients. We plotted the patients' SpO2 value time-courses and assessed desaturation in 6,228 patients. The crude overall incidence (95%CI) for desaturation was 11.1% (9.4-13.1) in the pediatric patients and 0.9% (0.6-1.2) in the adults. The crude incidence of desaturation in the hypoxic pediatric patients was 2.5 times the risk in the nonhypoxic patients: risk ratio (RR) 2.5 (1.8- 3.5), p < 0.001. The risk of desaturation in the hypoxic adult patients was 20.1 times the risk in the nonhypoxic adult patients: RR 20.1 (10.3-39.2), p < 0.001. When the patients were separately stratified by American Society of Anesthesiologists Physical Status (ASA-PS) and by age, the directly adjusted risk-ratio (RRS) showed that the hypoxic pediatric patients had 1.8 and 1.6 times the risk in the nonhypoxic pediatric patients: ASA-PS adjusted RRS 1.6 (1.8-2.2), p < 0.001; age-adjusted RRS 1.8 (1.3-2.5), p < 0.001, and the hypoxic adult patients had 13.8 times the risk in the nonhypoxic adult patients: RRS 13.8 (6.9-27.6), p < 0.001. A pulse-oximeter check before the start of general anesthesia could ensure timely preparation to avoid intraoperative desaturation.
AB - We investigated the incidence of desaturation during general anesthesia in preoperatively hypoxic ( < 92%), and nonhypoxic (≥ 92%) pediatric (n=1,090) and adult (n=5,138) patients. We plotted the patients' SpO2 value time-courses and assessed desaturation in 6,228 patients. The crude overall incidence (95%CI) for desaturation was 11.1% (9.4-13.1) in the pediatric patients and 0.9% (0.6-1.2) in the adults. The crude incidence of desaturation in the hypoxic pediatric patients was 2.5 times the risk in the nonhypoxic patients: risk ratio (RR) 2.5 (1.8- 3.5), p < 0.001. The risk of desaturation in the hypoxic adult patients was 20.1 times the risk in the nonhypoxic adult patients: RR 20.1 (10.3-39.2), p < 0.001. When the patients were separately stratified by American Society of Anesthesiologists Physical Status (ASA-PS) and by age, the directly adjusted risk-ratio (RRS) showed that the hypoxic pediatric patients had 1.8 and 1.6 times the risk in the nonhypoxic pediatric patients: ASA-PS adjusted RRS 1.6 (1.8-2.2), p < 0.001; age-adjusted RRS 1.8 (1.3-2.5), p < 0.001, and the hypoxic adult patients had 13.8 times the risk in the nonhypoxic adult patients: RRS 13.8 (6.9-27.6), p < 0.001. A pulse-oximeter check before the start of general anesthesia could ensure timely preparation to avoid intraoperative desaturation.
KW - Adult
KW - Desaturation incidence
KW - General anesthesia
KW - Pediatric
KW - Pulse oximetry
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M3 - Article
C2 - 30369603
AN - SCOPUS:85055616198
SN - 0386-300X
VL - 72
SP - 467
EP - 478
JO - Acta medica Okayama
JF - Acta medica Okayama
IS - 5
ER -