The Wittig Reaction of Benzofuran-2,3-diones

Yasuo Takeuchi; Tominari Choshi; Hideo Tomozane; Hirokazu Yoshida; Masatoshi Yamato

doi:10.1248/cpb.38.2265

The Wittig Reaction of Benzofuran-2,3-diones

Yasuo Takeuchi, Tominari Choshi, Hideo Tomozane, Hirokazu Yoshida, Masatoshi Yamato

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

The Wittig reaction of benzofuran-2,3-diones (2), cyclic ac-ketoesters was examined. The reaction of 2 having an electron-donating substituent on the aromatic ring with a stable ylide afforded not 3-alkylidene-2(3//)-benzofuranones (4) but 2-alkylidene-3(2//)-benzofuranones (1) with high regioselectivity.

Original language	English
Pages (from-to)	2265-2267
Number of pages	3
Journal	Chemical and Pharmaceutical Bulletin
Volume	38
Issue number	8
DOIs	https://doi.org/10.1248/cpb.38.2265
Publication status	Published - 1990

Keywords

3-dione Wittig reaction regioselectivity
a-ketoester benzofuran-2

ASJC Scopus subject areas

Chemistry(all)
Drug Discovery

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abstract = "The Wittig reaction of benzofuran-2,3-diones (2), cyclic ac-ketoesters was examined. The reaction of 2 having an electron-donating substituent on the aromatic ring with a stable ylide afforded not 3-alkylidene-2(3//)-benzofuranones (4) but 2-alkylidene-3(2//)-benzofuranones (1) with high regioselectivity.",

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T1 - The Wittig Reaction of Benzofuran-2,3-diones

AU - Takeuchi, Yasuo

AU - Choshi, Tominari

AU - Tomozane, Hideo

AU - Yoshida, Hirokazu

AU - Yamato, Masatoshi

PY - 1990

Y1 - 1990

N2 - The Wittig reaction of benzofuran-2,3-diones (2), cyclic ac-ketoesters was examined. The reaction of 2 having an electron-donating substituent on the aromatic ring with a stable ylide afforded not 3-alkylidene-2(3//)-benzofuranones (4) but 2-alkylidene-3(2//)-benzofuranones (1) with high regioselectivity.

AB - The Wittig reaction of benzofuran-2,3-diones (2), cyclic ac-ketoesters was examined. The reaction of 2 having an electron-donating substituent on the aromatic ring with a stable ylide afforded not 3-alkylidene-2(3//)-benzofuranones (4) but 2-alkylidene-3(2//)-benzofuranones (1) with high regioselectivity.

KW - 3-dione Wittig reaction regioselectivity

KW - a-ketoester benzofuran-2

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The Wittig Reaction of Benzofuran-2,3-diones

Abstract

Keywords

ASJC Scopus subject areas

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