TY - JOUR
T1 - Therapeutic use of chemokines
AU - Hogaboam, Cory M.
AU - Bone-Larson, Cynthia
AU - Matsukawa, Akihiro
AU - Steinhauser, Matthew L.
AU - Blease, Kate
AU - Lukacs, Nicholas W.
AU - Kunkel, Steven L.
PY - 2000/4
Y1 - 2000/4
N2 - Chemokines are involved in a number of pathological processes, and therefore represent important targets. However, it has also become apparent that chemokines have exciting therapeutic applications in inflammatory, infectious and cancer-related diseases. The following review will highlight the application of novel therapies including viral-encoded, recombinant, and genetically engineered chemokines to a number of diseases or disorders. Advances in the application of novel chemokine delivery procedures both at the research bench and the clinical bedside will also be discussed. Overall, the utilization of chemokines to prevent and treat disease has tremendous potential.
AB - Chemokines are involved in a number of pathological processes, and therefore represent important targets. However, it has also become apparent that chemokines have exciting therapeutic applications in inflammatory, infectious and cancer-related diseases. The following review will highlight the application of novel therapies including viral-encoded, recombinant, and genetically engineered chemokines to a number of diseases or disorders. Advances in the application of novel chemokine delivery procedures both at the research bench and the clinical bedside will also be discussed. Overall, the utilization of chemokines to prevent and treat disease has tremendous potential.
UR - http://www.scopus.com/inward/record.url?scp=0034091363&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0034091363&partnerID=8YFLogxK
U2 - 10.2174/1381612003400605
DO - 10.2174/1381612003400605
M3 - Article
C2 - 10788602
AN - SCOPUS:0034091363
SN - 1381-6128
VL - 6
SP - 651
EP - 663
JO - Current Pharmaceutical Design
JF - Current Pharmaceutical Design
IS - 6
ER -
