Three new taxanes with the 10-alkoxy group from the heartwood of Taxus cuspidata

Mei Dong; Man Li Zhang; Yu Fang Wang; Xi Ping Zhang; Cun Fang Li; Qing Wen Shi; Bin Cong; Hiromasa Kiyota

doi:10.1271/bbb.70210

Three new taxanes with the 10-alkoxy group from the heartwood of Taxus cuspidata

Mei Dong, Man Li Zhang, Yu Fang Wang, Xi Ping Zhang, Cun Fang Li, Qing Wen Shi, Bin Cong, Hiromasa Kiyota

Research output: Contribution to journal › Article › peer-review

4 Citations (Scopus)

Abstract

Three novel taxanes with the 10-alkoxy group were isolated from heartwood of Taxus cuspidata. The structures were identified as 2α,14β- diacetoxy-10β-ethoxytaxa-11,4(20)-dien-5α-ol (1), 2α,14β-diacetoxy-10β-methoxytaxa-11,4(20)-dien-5α-ol (2), and 2α-acetoxy-10β-ethoxytaxa-11,4(20)-diene-5α,14β-diol (3) on the basis of spectroscopic analysis. These are the first taxanes with an alkoxy moiety on the skeleton.

Original language	English
Pages (from-to)	2087-2090
Number of pages	4
Journal	Bioscience, Biotechnology and Biochemistry
Volume	71
Issue number	8
DOIs	https://doi.org/10.1271/bbb.70210
Publication status	Published - 2007
Externally published	Yes

Keywords

Alkoxy taxanes
Taxaceae
Taxane
Taxus cuspidata
Yew

ASJC Scopus subject areas

Biotechnology
Analytical Chemistry
Biochemistry
Applied Microbiology and Biotechnology
Molecular Biology
Organic Chemistry

Access to Document

10.1271/bbb.70210

Cite this

@article{b83b7c534ed645d79ee419bda8b96290,

title = "Three new taxanes with the 10-alkoxy group from the heartwood of Taxus cuspidata",

abstract = "Three novel taxanes with the 10-alkoxy group were isolated from heartwood of Taxus cuspidata. The structures were identified as 2α,14β- diacetoxy-10β-ethoxytaxa-11,4(20)-dien-5α-ol (1), 2α,14β-diacetoxy-10β-methoxytaxa-11,4(20)-dien-5α-ol (2), and 2α-acetoxy-10β-ethoxytaxa-11,4(20)-diene-5α,14β-diol (3) on the basis of spectroscopic analysis. These are the first taxanes with an alkoxy moiety on the skeleton.",

keywords = "Alkoxy taxanes, Taxaceae, Taxane, Taxus cuspidata, Yew",

author = "Mei Dong and Zhang, {Man Li} and Wang, {Yu Fang} and Zhang, {Xi Ping} and Li, {Cun Fang} and Shi, {Qing Wen} and Bin Cong and Hiromasa Kiyota",

year = "2007",

doi = "10.1271/bbb.70210",

language = "English",

volume = "71",

pages = "2087--2090",

journal = "Bioscience, Biotechnology and Biochemistry",

issn = "0916-8451",

publisher = "Japan Society for Bioscience Biotechnology and Agrochemistry",

number = "8",

}

TY - JOUR

T1 - Three new taxanes with the 10-alkoxy group from the heartwood of Taxus cuspidata

AU - Dong, Mei

AU - Zhang, Man Li

AU - Wang, Yu Fang

AU - Zhang, Xi Ping

AU - Li, Cun Fang

AU - Shi, Qing Wen

AU - Cong, Bin

AU - Kiyota, Hiromasa

PY - 2007

Y1 - 2007

N2 - Three novel taxanes with the 10-alkoxy group were isolated from heartwood of Taxus cuspidata. The structures were identified as 2α,14β- diacetoxy-10β-ethoxytaxa-11,4(20)-dien-5α-ol (1), 2α,14β-diacetoxy-10β-methoxytaxa-11,4(20)-dien-5α-ol (2), and 2α-acetoxy-10β-ethoxytaxa-11,4(20)-diene-5α,14β-diol (3) on the basis of spectroscopic analysis. These are the first taxanes with an alkoxy moiety on the skeleton.

AB - Three novel taxanes with the 10-alkoxy group were isolated from heartwood of Taxus cuspidata. The structures were identified as 2α,14β- diacetoxy-10β-ethoxytaxa-11,4(20)-dien-5α-ol (1), 2α,14β-diacetoxy-10β-methoxytaxa-11,4(20)-dien-5α-ol (2), and 2α-acetoxy-10β-ethoxytaxa-11,4(20)-diene-5α,14β-diol (3) on the basis of spectroscopic analysis. These are the first taxanes with an alkoxy moiety on the skeleton.

KW - Alkoxy taxanes

KW - Taxaceae

KW - Taxane

KW - Taxus cuspidata

KW - Yew

UR - http://www.scopus.com/inward/record.url?scp=36148956568&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=36148956568&partnerID=8YFLogxK

U2 - 10.1271/bbb.70210

DO - 10.1271/bbb.70210

M3 - Article

C2 - 17690449

AN - SCOPUS:36148956568

SN - 0916-8451

VL - 71

SP - 2087

EP - 2090

JO - Bioscience, Biotechnology and Biochemistry

JF - Bioscience, Biotechnology and Biochemistry

IS - 8

ER -

Three new taxanes with the 10-alkoxy group from the heartwood of Taxus cuspidata

Abstract

Keywords

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this