Tolerance of Drosophila flies to ibotenic acid poisons in mushrooms

Nobuko Tuno, Kazuo H. Takahashi, Hiroshi Yamashita, Naoya Osawa, Chihiro Tanaka

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

The mushroom genus Amanita has a spectrum of chemical compounds affecting survival and performance of animals. Ibotenic acid is one of such compounds found in some Amanita mushrooms. We studied the effects of ibotenic acid and its derivative, muscimol, on egg-to-pupa survival, pupation time, and pupal size in five Drosophila species (Diptera: Drosophilidae), Drosophila bizonata, Drosophila angularis, Drosophila brachynephros, Drosophila immigrans, and Drosophila melanogaster. The first three species are mycophagous and use a wide range of mushrooms for breeding, whereas D. immigrans and D. melanogaster are frugivorous. We reared fly larvae on artificial medium with 500, 250, 125, and 62.5 μg/ml of ibotenic acid and/or musimol. The three mycophagous species were not susceptible to ibotenic acid, whereas the two frugivorous species were affected. In experiments with D. melanogaster, muscimol was less toxic than ibotenic acid.

Original languageEnglish
Pages (from-to)311-317
Number of pages7
JournalJournal of Chemical Ecology
Volume33
Issue number2
DOIs
Publication statusPublished - Feb 2007
Externally publishedYes

Keywords

  • Amanita
  • Drosophila
  • Ibotenic acid
  • Mycophagy
  • Susceptibility

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Biochemistry

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