Transition of mechanical property of porous alginate scaffold with cells during culture period

Shinji Sakai; Hiroki Masuhara; Yusuke Yamada; Tsutomu Ono; Hiroyuki Ijima; Koei Kawakami

doi:10.1263/jbb.100.127

Transition of mechanical property of porous alginate scaffold with cells during culture period

Shinji Sakai, Hiroki Masuhara, Yusuke Yamada, Tsutomu Ono, Hiroyuki Ijima, Koei Kawakami

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

The rupture forces of porous alginate scaffolds seeded with hepatocytes or fibroblast-like cells increased during 3 d of culture and then decreased. The phenomenon was independent of the number of viable cells within the scaffolds, but dependent on protein adsorption to the alginate as well as a reduction in the degree of crosslinks of the calcium-alginate gel.

Original language	English
Pages (from-to)	127-129
Number of pages	3
Journal	Journal of Bioscience and Bioengineering
Volume	100
Issue number	1
DOIs	https://doi.org/10.1263/jbb.100.127
Publication status	Published - 2005
Externally published	Yes

Keywords

Alginate
Cell culture
Scaffold
Sponge
Tissue engineering

ASJC Scopus subject areas

Biotechnology
Bioengineering
Applied Microbiology and Biotechnology

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10.1263/jbb.100.127

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abstract = "The rupture forces of porous alginate scaffolds seeded with hepatocytes or fibroblast-like cells increased during 3 d of culture and then decreased. The phenomenon was independent of the number of viable cells within the scaffolds, but dependent on protein adsorption to the alginate as well as a reduction in the degree of crosslinks of the calcium-alginate gel.",

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author = "Shinji Sakai and Hiroki Masuhara and Yusuke Yamada and Tsutomu Ono and Hiroyuki Ijima and Koei Kawakami",

year = "2005",

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T1 - Transition of mechanical property of porous alginate scaffold with cells during culture period

AU - Sakai, Shinji

AU - Masuhara, Hiroki

AU - Yamada, Yusuke

AU - Ono, Tsutomu

AU - Ijima, Hiroyuki

AU - Kawakami, Koei

PY - 2005

Y1 - 2005

N2 - The rupture forces of porous alginate scaffolds seeded with hepatocytes or fibroblast-like cells increased during 3 d of culture and then decreased. The phenomenon was independent of the number of viable cells within the scaffolds, but dependent on protein adsorption to the alginate as well as a reduction in the degree of crosslinks of the calcium-alginate gel.

AB - The rupture forces of porous alginate scaffolds seeded with hepatocytes or fibroblast-like cells increased during 3 d of culture and then decreased. The phenomenon was independent of the number of viable cells within the scaffolds, but dependent on protein adsorption to the alginate as well as a reduction in the degree of crosslinks of the calcium-alginate gel.

KW - Alginate

KW - Cell culture

KW - Scaffold

KW - Sponge

KW - Tissue engineering

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U2 - 10.1263/jbb.100.127

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M3 - Article

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AN - SCOPUS:27644519236

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JO - Journal of Bioscience and Bioengineering

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ER -

Transition of mechanical property of porous alginate scaffold with cells during culture period

Abstract

Keywords

ASJC Scopus subject areas

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