TY - JOUR
T1 - Transitions in morphological forms and rapid development of the asexual schizonts of Eimeria tenella through serial passaging in chicks
AU - Matsubayashi, Makoto
AU - Yamaguchi, Hiroki
AU - Hatta, Takeshi
AU - Kawahara, Fumiya
AU - Hatabu, Toshimitsu
AU - Iseki, Hiroshi
AU - Yamagishi, Junya
AU - Isobe, Takashi
AU - Teramoto, Isao
AU - Kaneko, Akira
AU - Kita, Kiyoshi
AU - Tsuji, Naotoshi
AU - Sasai, Kazumi
N1 - Funding Information:
This work was supported in part by Grants-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology (Grant No. 16 K08025 to M.M.) and the Joint Usage/Research Center (“Research Center for Zoonosis Control, Hokkaido University”).
Funding Information:
This work was supported in part by Grants-in-Aid for Scientific Research from the Ministry of Education, Culture, Sports, Science and Technology (Grant No. 16?K08025 to M.M.) and the Joint Usage/Research Center (?Research Center for Zoonosis Control, Hokkaido University?).
Publisher Copyright:
© 2019 Elsevier B.V.
PY - 2019/11
Y1 - 2019/11
N2 - Attenuated strains of avian Eimeria parasites, generated by the selection of precocious lines through serial passaging in chicks, have been used widely as live vaccines. Detailed morphological transitions including their life cycle depending on the passages remain poorly understood. Here, we showed early development and acceleration of transitions in morphological forms of the asexual schizonts of E. tenella that had been attenuated for virulence by serial passaging. Our results may be helpful in understanding parasitism, facilitating further molecular analyses such as comparative genomic or transcriptomic tests.
AB - Attenuated strains of avian Eimeria parasites, generated by the selection of precocious lines through serial passaging in chicks, have been used widely as live vaccines. Detailed morphological transitions including their life cycle depending on the passages remain poorly understood. Here, we showed early development and acceleration of transitions in morphological forms of the asexual schizonts of E. tenella that had been attenuated for virulence by serial passaging. Our results may be helpful in understanding parasitism, facilitating further molecular analyses such as comparative genomic or transcriptomic tests.
KW - Attenuation
KW - Eimeria tenella
KW - Schizont
KW - Virulence
UR - http://www.scopus.com/inward/record.url?scp=85070871485&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85070871485&partnerID=8YFLogxK
U2 - 10.1016/j.meegid.2019.103993
DO - 10.1016/j.meegid.2019.103993
M3 - Article
C2 - 31394291
AN - SCOPUS:85070871485
SN - 1567-1348
VL - 75
JO - Infection, Genetics and Evolution
JF - Infection, Genetics and Evolution
M1 - 103993
ER -
