TY - JOUR
T1 - Treatment for advanced squamous cell carcinoma of the lung
AU - Senoo, Satoru
AU - Ninomiya, Kiichiro
AU - Hotta, Katsuyuki
AU - Kiura, Katsuyuki
N1 - Publisher Copyright:
© 2018 The Japan Lung Cancer Society
PY - 2018
Y1 - 2018
N2 - Squamous cell carcinoma of the lung is associated with smoking in its development and com prises about 20-30% of all lung cancers. Treatment development for squamous cell carcinoma of the lung was gen erally stagnant for several years. However, in the 2010s, several clinical trials showing the efficacy of immune checkpoint inhibitors or chemotherapy such as nedaplatin combination have been reported, and the number o treatment options has significantly increased. In addition, new evidence, such as findings supporting combination therapy of chemotherapy and immune checkpoint inhibitors, is being accumulated. In this review, we will de scribe various clinical studies mainly involving non-elderly patients with a good performance status. In addition we will present the results of clinical trials newly reported in 2018.
AB - Squamous cell carcinoma of the lung is associated with smoking in its development and com prises about 20-30% of all lung cancers. Treatment development for squamous cell carcinoma of the lung was gen erally stagnant for several years. However, in the 2010s, several clinical trials showing the efficacy of immune checkpoint inhibitors or chemotherapy such as nedaplatin combination have been reported, and the number o treatment options has significantly increased. In addition, new evidence, such as findings supporting combination therapy of chemotherapy and immune checkpoint inhibitors, is being accumulated. In this review, we will de scribe various clinical studies mainly involving non-elderly patients with a good performance status. In addition we will present the results of clinical trials newly reported in 2018.
KW - Cytotoxic (anticancer) drug
KW - Immune checkpoint inhibitor
KW - Squamous cell carcinoma of the lung
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U2 - 10.2482/haigan.58.325
DO - 10.2482/haigan.58.325
M3 - Review article
AN - SCOPUS:85057082779
SN - 0386-9628
VL - 58
SP - 325
EP - 330
JO - Japanese Journal of Lung Cancer
JF - Japanese Journal of Lung Cancer
IS - 5
ER -