Two cases of high tibial osteotomy in patients with rheumatoid arthritis treated with biologic disease-modifying anti-rheumatic drugs

Yasuhiro Takahara; Keiichiro Nishida; Hirotaka Nakashima; Nobuaki Ochi; Yoichiro Uchida; Hisayoshi Kato; Satoru Itani; Makoto Nakamura; Yuichi Iwasaki; Yoshitaka Tsujimura

Two cases of high tibial osteotomy in patients with rheumatoid arthritis treated with biologic disease-modifying anti-rheumatic drugs

Yasuhiro Takahara, Keiichiro Nishida, Hirotaka Nakashima, Nobuaki Ochi, Yoichiro Uchida, Hisayoshi Kato, Satoru Itani, Makoto Nakamura, Yuichi Iwasaki, Yoshitaka Tsujimura

Research output: Contribution to journal › Article › peer-review

Abstract

High tibial osteotomy (HTO) procedure is generally contraindicated in rheumatoid arthritis (RA) patients because synovial inflammation may exacerbate joint damage post-surgery. The natural course of joint destruction in RA changed dramatically with new treatment strategies and the introduction of biologic disease-modifying anti-rheumatic drugs (bDMARDs). We report the cases of two RA patients who underwent HTO and whose disease activities were well controlled by bDMARDs. Despite their short follow-up periods, they showed acceptable objective and subjective clinical results. We believe that the combination of bDMARDs and HTO can be indicated for selected RA patients before total knee arthroplasty.

Original language	English
Pages (from-to)	537-542
Number of pages	6
Journal	Acta medica Okayama
Volume	73
Issue number	6
Publication status	Published - 2019

Keywords

Biologic DMARD
High tibial osteotomy
Knee surgery
Rheumatoid arthritis

ASJC Scopus subject areas

Biochemistry, Genetics and Molecular Biology(all)

Cite this

@article{08ffe929b0ee49a1b2ecf712c77794ee,

title = "Two cases of high tibial osteotomy in patients with rheumatoid arthritis treated with biologic disease-modifying anti-rheumatic drugs",

abstract = "High tibial osteotomy (HTO) procedure is generally contraindicated in rheumatoid arthritis (RA) patients because synovial inflammation may exacerbate joint damage post-surgery. The natural course of joint destruction in RA changed dramatically with new treatment strategies and the introduction of biologic disease-modifying anti-rheumatic drugs (bDMARDs). We report the cases of two RA patients who underwent HTO and whose disease activities were well controlled by bDMARDs. Despite their short follow-up periods, they showed acceptable objective and subjective clinical results. We believe that the combination of bDMARDs and HTO can be indicated for selected RA patients before total knee arthroplasty.",

keywords = "Biologic DMARD, High tibial osteotomy, Knee surgery, Rheumatoid arthritis",

author = "Yasuhiro Takahara and Keiichiro Nishida and Hirotaka Nakashima and Nobuaki Ochi and Yoichiro Uchida and Hisayoshi Kato and Satoru Itani and Makoto Nakamura and Yuichi Iwasaki and Yoshitaka Tsujimura",

year = "2019",

language = "English",

volume = "73",

pages = "537--542",

journal = "Acta medica Okayama",

issn = "0386-300X",

publisher = "Okayama University",

number = "6",

}

TY - JOUR

T1 - Two cases of high tibial osteotomy in patients with rheumatoid arthritis treated with biologic disease-modifying anti-rheumatic drugs

AU - Takahara, Yasuhiro

AU - Nishida, Keiichiro

AU - Nakashima, Hirotaka

AU - Ochi, Nobuaki

AU - Uchida, Yoichiro

AU - Kato, Hisayoshi

AU - Itani, Satoru

AU - Nakamura, Makoto

AU - Iwasaki, Yuichi

AU - Tsujimura, Yoshitaka

PY - 2019

Y1 - 2019

N2 - High tibial osteotomy (HTO) procedure is generally contraindicated in rheumatoid arthritis (RA) patients because synovial inflammation may exacerbate joint damage post-surgery. The natural course of joint destruction in RA changed dramatically with new treatment strategies and the introduction of biologic disease-modifying anti-rheumatic drugs (bDMARDs). We report the cases of two RA patients who underwent HTO and whose disease activities were well controlled by bDMARDs. Despite their short follow-up periods, they showed acceptable objective and subjective clinical results. We believe that the combination of bDMARDs and HTO can be indicated for selected RA patients before total knee arthroplasty.

AB - High tibial osteotomy (HTO) procedure is generally contraindicated in rheumatoid arthritis (RA) patients because synovial inflammation may exacerbate joint damage post-surgery. The natural course of joint destruction in RA changed dramatically with new treatment strategies and the introduction of biologic disease-modifying anti-rheumatic drugs (bDMARDs). We report the cases of two RA patients who underwent HTO and whose disease activities were well controlled by bDMARDs. Despite their short follow-up periods, they showed acceptable objective and subjective clinical results. We believe that the combination of bDMARDs and HTO can be indicated for selected RA patients before total knee arthroplasty.

KW - Biologic DMARD

KW - High tibial osteotomy

KW - Knee surgery

KW - Rheumatoid arthritis

UR - http://www.scopus.com/inward/record.url?scp=85077215448&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85077215448&partnerID=8YFLogxK

M3 - Article

C2 - 31871338

AN - SCOPUS:85077215448

SN - 0386-300X

VL - 73

SP - 537

EP - 542

JO - Acta medica Okayama

JF - Acta medica Okayama

IS - 6

ER -

Two cases of high tibial osteotomy in patients with rheumatoid arthritis treated with biologic disease-modifying anti-rheumatic drugs

Abstract

Keywords

ASJC Scopus subject areas

Other files and links

Fingerprint

Cite this