Tyrokeradines A and B, new bromotyrosine alkaloids with an imidazolyl-quinolinone moiety from a Verongid sponge

Hiroya Mukai; Takaaki Kubota; Kazuki Aoyama; Yuzuru Mikami; Jane Fromont; Jun'ichi Kobayashi

doi:10.1016/j.bmcl.2009.01.056

Tyrokeradines A and B, new bromotyrosine alkaloids with an imidazolyl-quinolinone moiety from a Verongid sponge

Hiroya Mukai, Takaaki Kubota, Kazuki Aoyama, Yuzuru Mikami, Jane Fromont, Jun'ichi Kobayashi

Research output: Contribution to journal › Article › peer-review

20 Citations (Scopus)

Abstract

Two new bromotyrosine alkaloids, tyrokeradines A (1) and B (2), with an imidazolyl-quinolinone moiety have been isolated from an Okinawan marine sponge of the order Verongida. The structures of 1 and 2 were elucidated on the basis of spectroscopic data.

Original language	English
Pages (from-to)	1337-1339
Number of pages	3
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	19
Issue number	5
DOIs	https://doi.org/10.1016/j.bmcl.2009.01.056
Publication status	Published - Mar 1 2009
Externally published	Yes

Keywords

Bromotyrosine alkaloids
Tyrokeradines A and B
Verongid sponge

ASJC Scopus subject areas

Biochemistry
Molecular Medicine
Molecular Biology
Pharmaceutical Science
Drug Discovery
Clinical Biochemistry
Organic Chemistry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.bmcl.2009.01.056

Cite this

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title = "Tyrokeradines A and B, new bromotyrosine alkaloids with an imidazolyl-quinolinone moiety from a Verongid sponge",

abstract = "Two new bromotyrosine alkaloids, tyrokeradines A (1) and B (2), with an imidazolyl-quinolinone moiety have been isolated from an Okinawan marine sponge of the order Verongida. The structures of 1 and 2 were elucidated on the basis of spectroscopic data.",

keywords = "Bromotyrosine alkaloids, Tyrokeradines A and B, Verongid sponge",

author = "Hiroya Mukai and Takaaki Kubota and Kazuki Aoyama and Yuzuru Mikami and Jane Fromont and Jun'ichi Kobayashi",

note = "Funding Information: We thank Mr. Z. Nagahama for his help with sponge collection, and Ms. S. Oka, Center for Instrumental Analysis, Hokkaido University, for measurements of ESIMS and ESIMS/MS. This work was supported by Grant-in-Aid for Science Research from the Ministry of Education, Culture, Sports, Science, and Technology of Japan.",

year = "2009",

month = mar,

day = "1",

doi = "10.1016/j.bmcl.2009.01.056",

language = "English",

volume = "19",

pages = "1337--1339",

journal = "Bioorganic and Medicinal Chemistry Letters",

issn = "0960-894X",

publisher = "Elsevier Limited",

number = "5",

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TY - JOUR

T1 - Tyrokeradines A and B, new bromotyrosine alkaloids with an imidazolyl-quinolinone moiety from a Verongid sponge

AU - Mukai, Hiroya

AU - Kubota, Takaaki

AU - Aoyama, Kazuki

AU - Mikami, Yuzuru

AU - Fromont, Jane

AU - Kobayashi, Jun'ichi

N1 - Funding Information: We thank Mr. Z. Nagahama for his help with sponge collection, and Ms. S. Oka, Center for Instrumental Analysis, Hokkaido University, for measurements of ESIMS and ESIMS/MS. This work was supported by Grant-in-Aid for Science Research from the Ministry of Education, Culture, Sports, Science, and Technology of Japan.

PY - 2009/3/1

Y1 - 2009/3/1

N2 - Two new bromotyrosine alkaloids, tyrokeradines A (1) and B (2), with an imidazolyl-quinolinone moiety have been isolated from an Okinawan marine sponge of the order Verongida. The structures of 1 and 2 were elucidated on the basis of spectroscopic data.

AB - Two new bromotyrosine alkaloids, tyrokeradines A (1) and B (2), with an imidazolyl-quinolinone moiety have been isolated from an Okinawan marine sponge of the order Verongida. The structures of 1 and 2 were elucidated on the basis of spectroscopic data.

KW - Bromotyrosine alkaloids

KW - Tyrokeradines A and B

KW - Verongid sponge

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DO - 10.1016/j.bmcl.2009.01.056

M3 - Article

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AN - SCOPUS:60849100803

SN - 0960-894X

VL - 19

SP - 1337

EP - 1339

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 5

ER -

Tyrokeradines A and B, new bromotyrosine alkaloids with an imidazolyl-quinolinone moiety from a Verongid sponge

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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