Abstract
We have used silkworms, larva of Bombyx mori, to investigate host-pathogen interactions. Silkworms have several advantages, such as high availability of a large number of animals and ease of injection of quantitative amounts of samples. Human pathogenic bacteria such as Staphylococcus aureus, Streptococcus pyogenes, or Pseudomonas aeruginosa kill silkworms. In this review, I would like to summarize our approach identifying S. aureus virulence factors by using the silkworm infection model.
| Original language | English |
|---|---|
| Pages (from-to) | 30-33 |
| Number of pages | 4 |
| Journal | Drug Discoveries and Therapeutics |
| Volume | 10 |
| Issue number | 1 |
| DOIs | |
| Publication status | Published - 2016 |
| Externally published | Yes |
Keywords
- Bombyx mori
- Infection model
- Staphylococcus aureus
- Virulence factors
ASJC Scopus subject areas
- Medicine(all)