Understanding of bacterial virulence using the silkworm infection model

Research output: Contribution to journalReview articlepeer-review

13 Citations (Scopus)


We have used silkworms, larva of Bombyx mori, to investigate host-pathogen interactions. Silkworms have several advantages, such as high availability of a large number of animals and ease of injection of quantitative amounts of samples. Human pathogenic bacteria such as Staphylococcus aureus, Streptococcus pyogenes, or Pseudomonas aeruginosa kill silkworms. In this review, I would like to summarize our approach identifying S. aureus virulence factors by using the silkworm infection model.

Original languageEnglish
Pages (from-to)30-33
Number of pages4
JournalDrug Discoveries and Therapeutics
Issue number1
Publication statusPublished - 2016
Externally publishedYes


  • Bombyx mori
  • Infection model
  • Staphylococcus aureus
  • Virulence factors

ASJC Scopus subject areas

  • Medicine(all)


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