Uptake of rosuvastatin by isolated rat hepatocytes: Comparison with pravastatin

Medicine & Life Sciences

• 3-hydroxy-3-methylglutaryl-coenzyme A 4%
• Active Biological Transport 4%
• Adenosine Triphosphate 5%
• Anions 4%
• Hepatocytes 51%
• Ions 3%
• Kinetics 2%
• Lipids 2%
• Liver 5%
• Organic Anion Transporters 5%
• Oxidoreductases 3%
• Pharmaceutical Preparations 4%
• Pravastatin 80%
• Rosuvastatin Calcium 5%
• Sodium Chloride 4%
• Sulfobromophthalein 5%

Chemical Compounds

• Bromosulfophthalein 6%
• Clearance 12%
• Coenzyme A 4%
• Drug 6%
• Inhibition Constant (Ki) 5%
• Organic Anion 9%
• Passive Diffusion 5%
• Pravastatin 100%
• Protein 1%
• Rosuvastatin 6%
• Sodium Atom 2%
• Vmax 8%