Urinary excretion of aquaporin-2 in term and preterm infants

Hirokazu Tsukahara; Ikue Hata; Kyoichi Sekine; Masakazu Miura; Keishi Hata; Yasushi Fujii; Mitsufumi Mayumi

doi:10.1016/S0378-3782(97)00072-8

Urinary excretion of aquaporin-2 in term and preterm infants

Hirokazu Tsukahara, Ikue Hata, Kyoichi Sekine, Masakazu Miura, Keishi Hata, Yasushi Fujii, Mitsufumi Mayumi

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

Aquaporin-2 (AQP-2) is a vasopressin-regulated water channel of the renal collecting duct and is excreted in human urine. We measured the urinary excretion of AQP-2 by radioimmunoassay in 14 term and 12 preterm infants aged 1 month. Excretion of AQP-2 was low compared with adults, and correlated significantly with urine osmolality in preterm infants. Our results demonstrate that AQP-2 water channels are expressed in the renal collecting duct of both term and preterm infants.

Original language	English
Pages (from-to)	31-37
Number of pages	7
Journal	Early Human Development
Volume	51
Issue number	1
DOIs	https://doi.org/10.1016/S0378-3782(97)00072-8
Publication status	Published - Apr 17 1998
Externally published	Yes

Keywords

Aquaporin-2
Infants
Urine
Vasopressin
Water balance

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynaecology

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10.1016/S0378-3782(97)00072-8

Cite this

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abstract = "Aquaporin-2 (AQP-2) is a vasopressin-regulated water channel of the renal collecting duct and is excreted in human urine. We measured the urinary excretion of AQP-2 by radioimmunoassay in 14 term and 12 preterm infants aged 1 month. Excretion of AQP-2 was low compared with adults, and correlated significantly with urine osmolality in preterm infants. Our results demonstrate that AQP-2 water channels are expressed in the renal collecting duct of both term and preterm infants.",

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AU - Tsukahara, Hirokazu

AU - Hata, Ikue

AU - Sekine, Kyoichi

AU - Miura, Masakazu

AU - Hata, Keishi

AU - Fujii, Yasushi

AU - Mayumi, Mitsufumi

PY - 1998/4/17

Y1 - 1998/4/17

N2 - Aquaporin-2 (AQP-2) is a vasopressin-regulated water channel of the renal collecting duct and is excreted in human urine. We measured the urinary excretion of AQP-2 by radioimmunoassay in 14 term and 12 preterm infants aged 1 month. Excretion of AQP-2 was low compared with adults, and correlated significantly with urine osmolality in preterm infants. Our results demonstrate that AQP-2 water channels are expressed in the renal collecting duct of both term and preterm infants.

AB - Aquaporin-2 (AQP-2) is a vasopressin-regulated water channel of the renal collecting duct and is excreted in human urine. We measured the urinary excretion of AQP-2 by radioimmunoassay in 14 term and 12 preterm infants aged 1 month. Excretion of AQP-2 was low compared with adults, and correlated significantly with urine osmolality in preterm infants. Our results demonstrate that AQP-2 water channels are expressed in the renal collecting duct of both term and preterm infants.

KW - Aquaporin-2

KW - Infants

KW - Urine

KW - Vasopressin

KW - Water balance

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Urinary excretion of aquaporin-2 in term and preterm infants

Abstract

Keywords

ASJC Scopus subject areas

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