Urinary N‐acetyl‐beta‐D‐glucosaminidase excretion in term and preterm neonates

H. TSUKAHARA; C. HORI; S. TSUCHIDA; M. HIRAOKA; M. SUDO; S. HARUKI; F. SUEHIRO

doi:10.1111/j.1440-1754.1994.tb00729.x

Urinary N‐acetyl‐beta‐D‐glucosaminidase excretion in term and preterm neonates

H. TSUKAHARA, C. HORI, S. TSUCHIDA, M. HIRAOKA, M. SUDO, S. HARUKI, F. SUEHIRO

Research output: Contribution to journal › Article › peer-review

12 Citations (Scopus)

Abstract

Urinary N‐acetyl‐beta‐D‐glucosaminidase (NAG) excretion was measured in term and preterm neonates on days 1, 4, 7, 14 and 28 of life. Urinary NAG showed a peak level on day 4 or 7 in these infants. In addition, it tended to be higher with the degree of prematurity. In sick preterms who were depressed at birth and had respiratory failure, the NAG activity was further elevated during the first 2 weeks, suggesting the presence of renal tubular injury in this period. These observations thus suggest that urinary NAG may be a sensitive measure of renal maturation or damage in neonates.

Original language	English
Pages (from-to)	536-538
Number of pages	3
Journal	Journal of Paediatrics and Child Health
Volume	30
Issue number	6
DOIs	https://doi.org/10.1111/j.1440-1754.1994.tb00729.x
Publication status	Published - Dec 1994
Externally published	Yes

Keywords

N‐acetyl‐beta‐D‐glucosaminidase
neonates
prematurity
renal tubular damage

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health

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10.1111/j.1440-1754.1994.tb00729.x

Cite this

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title = "Urinary N‐acetyl‐beta‐D‐glucosaminidase excretion in term and preterm neonates",

abstract = "Urinary N‐acetyl‐beta‐D‐glucosaminidase (NAG) excretion was measured in term and preterm neonates on days 1, 4, 7, 14 and 28 of life. Urinary NAG showed a peak level on day 4 or 7 in these infants. In addition, it tended to be higher with the degree of prematurity. In sick preterms who were depressed at birth and had respiratory failure, the NAG activity was further elevated during the first 2 weeks, suggesting the presence of renal tubular injury in this period. These observations thus suggest that urinary NAG may be a sensitive measure of renal maturation or damage in neonates.",

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T1 - Urinary N‐acetyl‐beta‐D‐glucosaminidase excretion in term and preterm neonates

AU - TSUKAHARA, H.

AU - HORI, C.

AU - TSUCHIDA, S.

AU - HIRAOKA, M.

AU - SUDO, M.

AU - HARUKI, S.

AU - SUEHIRO, F.

PY - 1994/12

Y1 - 1994/12

N2 - Urinary N‐acetyl‐beta‐D‐glucosaminidase (NAG) excretion was measured in term and preterm neonates on days 1, 4, 7, 14 and 28 of life. Urinary NAG showed a peak level on day 4 or 7 in these infants. In addition, it tended to be higher with the degree of prematurity. In sick preterms who were depressed at birth and had respiratory failure, the NAG activity was further elevated during the first 2 weeks, suggesting the presence of renal tubular injury in this period. These observations thus suggest that urinary NAG may be a sensitive measure of renal maturation or damage in neonates.

AB - Urinary N‐acetyl‐beta‐D‐glucosaminidase (NAG) excretion was measured in term and preterm neonates on days 1, 4, 7, 14 and 28 of life. Urinary NAG showed a peak level on day 4 or 7 in these infants. In addition, it tended to be higher with the degree of prematurity. In sick preterms who were depressed at birth and had respiratory failure, the NAG activity was further elevated during the first 2 weeks, suggesting the presence of renal tubular injury in this period. These observations thus suggest that urinary NAG may be a sensitive measure of renal maturation or damage in neonates.

KW - N‐acetyl‐beta‐D‐glucosaminidase

KW - neonates

KW - prematurity

KW - renal tubular damage

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Urinary N‐acetyl‐beta‐D‐glucosaminidase excretion in term and preterm neonates

Abstract

Keywords

ASJC Scopus subject areas

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