Shiro Hinotsu, Hideyuki Akaza

Research output: Contribution to journalReview articlepeer-review


We reviewed comparative clinical studies for prostate cancer and bladder cancer performed in Japan. A systematic search was done using PubMed and Icyushi WEB to find randomized clinical trials and the result was verified. Each manuscript was summarized according to the seven items of stage, entry period, exposure, endpoint, sample size, method of randomization and result. Forty reports were found as randomized clinical trials for prostate cancer, and sixty-two reports were identified for bladder cancer. Most exposures for advanced prostate cancer were hormonal therapy involving intravesical instillation after transurethral resection for superficial bladder cancer. At minimum, we have clarified that large scale randomized trials have been conducted in Japan for both prostate cancer and bladder cancer.

Original languageEnglish
Pages (from-to)1549-1569
Number of pages21
JournalGan to kagaku ryoho. Cancer & chemotherapy
Issue number9
Publication statusPublished - Sept 2002

ASJC Scopus subject areas

  • Oncology
  • Cancer Research


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