Usefulness of indocyanine green angiography in detecting the location of choroidal neovascularization

C. Shiragami, F. Shiraga, S. Yokoe, Y. Okuda, Y. Ojima, N. Matsuo

Research output: Contribution to journalArticlepeer-review


Choroidal neovascularization (CNV) grows in the subretinal space, subpigment epithelial space or both. Identification of their location is essential in planning the therapy including subretinal surgery. We performed indocyanine green (ICG) angiography in 8 eyes of age related macular degeneration and in 2 eyes of idiopathic neovascularization. All the eyes underwent submacular surgery. CNVs located in the subretinal space were characterized by the distinct visibility of neovascular vessels in the early angiographic phase. The CNV and its stalk were surrounded by hypofluorescent rim throughout the phrases. In CNVs located in the subpigment epithelial space, the whole area of CNVs appeared as hypofluorescent in the early phase. The degree of hyperfluorescence and the time of its appearance within the area of CNVs differed according to the activity of CNVs. ICG angiography was thus useful in locating the CNVs.

Original languageEnglish
Pages (from-to)1239-1244
Number of pages6
JournalJapanese Journal of Clinical Ophthalmology
Issue number6
Publication statusPublished - Jan 1 1996

ASJC Scopus subject areas

  • Ophthalmology


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