TY - JOUR
T1 - Vibrio vulnificus induces macrophage apoptosis in vitro and in vivo
AU - Kashimoto, Takashige
AU - Ueno, Shunji
AU - Hanajima, Miyuki
AU - Hayashi, Hisae
AU - Akeda, Yukihiro
AU - Miyoshi, Shinichi
AU - Hongo, Toshiharu
AU - Honda, Takeshi
AU - Susa, Nobuyuki
PY - 2003/1/1
Y1 - 2003/1/1
N2 - In this study, we compared the apoptotic activities of clinical and environmental isolates of Vibrio vulnificus toward macrophages in vitro and in vivo. The clinical isolates induced apoptosis in macrophage-like cells in vitro and in macrophages in vivo. This suggests that macrophage apoptosis may be important for the clinical virulence of V. vulnificus.
AB - In this study, we compared the apoptotic activities of clinical and environmental isolates of Vibrio vulnificus toward macrophages in vitro and in vivo. The clinical isolates induced apoptosis in macrophage-like cells in vitro and in macrophages in vivo. This suggests that macrophage apoptosis may be important for the clinical virulence of V. vulnificus.
UR - http://www.scopus.com/inward/record.url?scp=0037218329&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0037218329&partnerID=8YFLogxK
U2 - 10.1128/IAI.71.1.533-535.2003
DO - 10.1128/IAI.71.1.533-535.2003
M3 - Article
C2 - 12496206
AN - SCOPUS:0037218329
SN - 0019-9567
VL - 71
SP - 533
EP - 535
JO - Infection and Immunity
JF - Infection and Immunity
IS - 1
ER -