Visualisation method of spatial interictal discharges in temporal epilepsy patients using magneto-encephalogram

A. Kandori; H. Oe; K. Miyashita; H. Date; N. Yamada; H. Naritomi; Y. Chiba; M. Murakami; T. Miyashita; K. Tsukada

doi:10.1007/BF02344215

Visualisation method of spatial interictal discharges in temporal epilepsy patients using magneto-encephalogram

A. Kandori, H. Oe, K. Miyashita, H. Date, N. Yamada, H. Naritomi, Y. Chiba, M. Murakami, T. Miyashita, K. Tsukada

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

Abstract

The aim of the study was to develop a method for investigating how interictal epileptic discharges in temporal epilepsy patients are activated spatially. The activity was measured using magneto-encephalography (MEG). The MEG data were used to produce a current-arrow map that reflected the topographic distribution of the electrical current for each peak epileptic waveform. A large current distribution was obtained that appeared to be contained in the limbic structure, in each temporal lobe. The large current orientation indicated two opposite directions. Furthermore, the decrease in the maximum strength of the current-arrow, depending on the medication (e.g. the decrease from 11 to 6pT m^-1 in the left temporal lobe (contralateral stimuli)), suggested that the discharge distributions could be used to verify the efficacy of medication. Thus the topographical visualisation method could be a new strategy for diagnosis in temporal epilepsy patients.

Original language	English
Pages (from-to)	327-331
Number of pages	5
Journal	Medical and Biological Engineering and Computing
Volume	40
Issue number	3
DOIs	https://doi.org/10.1007/BF02344215
Publication status	Published - 2002
Externally published	Yes

Keywords

Current-arrow map
Interictal discharge
Kindling phenomenon
Limbic structure
Magneto-encephalogram
Temporal epilepsy

ASJC Scopus subject areas

Biomedical Engineering
Computer Science Applications

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10.1007/BF02344215

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title = "Visualisation method of spatial interictal discharges in temporal epilepsy patients using magneto-encephalogram",

abstract = "The aim of the study was to develop a method for investigating how interictal epileptic discharges in temporal epilepsy patients are activated spatially. The activity was measured using magneto-encephalography (MEG). The MEG data were used to produce a current-arrow map that reflected the topographic distribution of the electrical current for each peak epileptic waveform. A large current distribution was obtained that appeared to be contained in the limbic structure, in each temporal lobe. The large current orientation indicated two opposite directions. Furthermore, the decrease in the maximum strength of the current-arrow, depending on the medication (e.g. the decrease from 11 to 6pT m-1 in the left temporal lobe (contralateral stimuli)), suggested that the discharge distributions could be used to verify the efficacy of medication. Thus the topographical visualisation method could be a new strategy for diagnosis in temporal epilepsy patients.",

keywords = "Current-arrow map, Interictal discharge, Kindling phenomenon, Limbic structure, Magneto-encephalogram, Temporal epilepsy",

author = "A. Kandori and H. Oe and K. Miyashita and H. Date and N. Yamada and H. Naritomi and Y. Chiba and M. Murakami and T. Miyashita and K. Tsukada",

note = "Funding Information: Acknowledgments{"} This study was supported by a Grant-in-Aid for Scientific Research No. 13072601, supported by the Ministry of Health, Labour and Welfare of Japan.",

year = "2002",

doi = "10.1007/BF02344215",

language = "English",

volume = "40",

pages = "327--331",

journal = "Medical and Biological Engineering and Computing",

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T1 - Visualisation method of spatial interictal discharges in temporal epilepsy patients using magneto-encephalogram

AU - Kandori, A.

AU - Oe, H.

AU - Miyashita, K.

AU - Date, H.

AU - Yamada, N.

AU - Naritomi, H.

AU - Chiba, Y.

AU - Murakami, M.

AU - Miyashita, T.

AU - Tsukada, K.

N1 - Funding Information: Acknowledgments" This study was supported by a Grant-in-Aid for Scientific Research No. 13072601, supported by the Ministry of Health, Labour and Welfare of Japan.

PY - 2002

Y1 - 2002

N2 - The aim of the study was to develop a method for investigating how interictal epileptic discharges in temporal epilepsy patients are activated spatially. The activity was measured using magneto-encephalography (MEG). The MEG data were used to produce a current-arrow map that reflected the topographic distribution of the electrical current for each peak epileptic waveform. A large current distribution was obtained that appeared to be contained in the limbic structure, in each temporal lobe. The large current orientation indicated two opposite directions. Furthermore, the decrease in the maximum strength of the current-arrow, depending on the medication (e.g. the decrease from 11 to 6pT m-1 in the left temporal lobe (contralateral stimuli)), suggested that the discharge distributions could be used to verify the efficacy of medication. Thus the topographical visualisation method could be a new strategy for diagnosis in temporal epilepsy patients.

AB - The aim of the study was to develop a method for investigating how interictal epileptic discharges in temporal epilepsy patients are activated spatially. The activity was measured using magneto-encephalography (MEG). The MEG data were used to produce a current-arrow map that reflected the topographic distribution of the electrical current for each peak epileptic waveform. A large current distribution was obtained that appeared to be contained in the limbic structure, in each temporal lobe. The large current orientation indicated two opposite directions. Furthermore, the decrease in the maximum strength of the current-arrow, depending on the medication (e.g. the decrease from 11 to 6pT m-1 in the left temporal lobe (contralateral stimuli)), suggested that the discharge distributions could be used to verify the efficacy of medication. Thus the topographical visualisation method could be a new strategy for diagnosis in temporal epilepsy patients.

KW - Current-arrow map

KW - Interictal discharge

KW - Kindling phenomenon

KW - Limbic structure

KW - Magneto-encephalogram

KW - Temporal epilepsy

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Visualisation method of spatial interictal discharges in temporal epilepsy patients using magneto-encephalogram

Abstract

Keywords

ASJC Scopus subject areas

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