Wax ester production from n-alkanes by Acinetobacter sp. strain M-1: Ultrastructure of cellular inclusions and role of acyl coenzyme a reductase

Takeru Ishige, Akio Tani, Keiji Takabe, Kazunori Kawasaki, Yasuyoshi Sakai, Nobuo Kato

Research output: Contribution to journalArticlepeer-review

57 Citations (Scopus)

Abstract

Acinetobacter sp. strain M-1 accumulated a large amount of wax esters from an n-alkane under nitrogen-limiting conditions. Under the optimized conditions with n-hexadecane as the substrate, the amount of hexadecyl hexadecanoate in the cells reached 0.17 g/g of cells (dry weight). Electron microscopic analysis revealed that multilayered disk-shaped intracellular inclusions were formed concomitant with wax ester formation. The contribution of acyl-CoA reductase to wax ester synthesis was evaluated by gene disruption analysis.

Original languageEnglish
Pages (from-to)1192-1195
Number of pages4
JournalApplied and environmental microbiology
Volume68
Issue number3
DOIs
Publication statusPublished - 2002
Externally publishedYes

ASJC Scopus subject areas

  • Biotechnology
  • Food Science
  • Applied Microbiology and Biotechnology
  • Ecology

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