Well-differentiated endocrine cell carcinoma of ileum treated by laparoscopy-assisted surgery - A case report

Shinsuke Sasada, Yasutomo Ojima, Masahiko Nishizaki, Masao Harano, Hiroyoshi Matsukawa, Hideki Aoki, Shigehiro Shiozaki, Satoshi Ohno, Motoki Ninomiya, Hiroo Matsuura, Norihisa Takakura

Research output: Contribution to journalArticlepeer-review


A 72-year-old woman presented at our hospital with a 1-year history of intermittent right lower abdominal pain. Colonoscopic examination revealed a submucosal tumor with a pitted surface in the terminal ileum. Histopathological diagnosis of the carcinoid tumor was made following biopsy. Blood serotonin and urine 5-hydroxy-indoleacetic acid levels were normal, and carcinoid syndrome was not detected. Enhanced abdominal computed tomography scan and 18F-fluorodeoxyglucose positron emission tomography failed to detect multiple lesions, lymph node swelling or distant metastasis. Laparoscopy-assisted ileocecal resection with lymph node dissection was performed. The resected specimen showed a submucosal tumor with a pitted surface 11 x 11 mm in size, located at the terminal ileum. Histopathological examination revealed a well-differentiated endocrine cell carcinoma with an invasion depth to the muscularis propria. Immunohistochemical analysis showed the tumor cells to be chromogranin A and CD56-positive. The patient had no sign of recurrence for 16 months.

Original languageEnglish
Pages (from-to)35-38
Number of pages4
JournalHiroshima Journal of Medical Sciences
Issue number2
Publication statusPublished - Jun 1 2010
Externally publishedYes


  • Endocrine cell carcinoma
  • Laparoscopy-assisted surgery
  • Small intestinal tumor

ASJC Scopus subject areas

  • Medicine(all)


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