Young adult-onset, very slowly progressive cognitive decline with spastic paraparesis in Alzheimer's disease with cotton wool plaques due to a novel presenilin1 G417S mutation

Tomoko Miki, Osamu Yokota, Takashi Haraguchi, Takeshi Ikeuchi, Bin Zhu, Shintaro Takenoshita, Seishi Terada, Norihito Yamada

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)
Original languageEnglish
Pages (from-to)19
Number of pages1
JournalActa Neuropathologica Communications
Issue number1
Publication statusPublished - Feb 12 2019


  • Alzheimer’s disease
  • Cotton wool plaques
  • Disease duration
  • Presenilin 1 mutation
  • Spastic paraparesis

ASJC Scopus subject areas

  • Pathology and Forensic Medicine
  • Clinical Neurology
  • Cellular and Molecular Neuroscience

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