Zamamidines A and B, new manzamine alkaloids from the sponge Amphimedon species

Yohei Takahashi; Takaaki Kubota; Jane Fromont; Jun'ichi Kobayashi

doi:10.1021/ol802251q

Zamamidines A and B, new manzamine alkaloids from the sponge Amphimedon species

Yohei Takahashi, Takaaki Kubota, Jane Fromont, Jun'ichi Kobayashi

Research output: Contribution to journal › Article › peer-review

35 Citations (Scopus)

Abstract

New manzamine alkaloids, zamamidines A (1) and B (2), have been isolated from an Okinawan marine sponge Amphimedon species. The structures and stereochemistry of 1 and 2 were elucidated from the spectroscopic data and conformational analysis. Zamamidines A (1) and B (2) are the first manzamine alkaloids possessing a second //-carboline ring via an ethylene unit at N-2 of manzamine H and 1,2,3,4-tetrahydromanzamine B, respectively.

Original language	English
Pages (from-to)	21-24
Number of pages	4
Journal	Organic Letters
Volume	11
Issue number	1
DOIs	https://doi.org/10.1021/ol802251q
Publication status	Published - Jan 1 2009
Externally published	Yes

ASJC Scopus subject areas

Biochemistry
Physical and Theoretical Chemistry
Organic Chemistry

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1021/ol802251q

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abstract = "New manzamine alkaloids, zamamidines A (1) and B (2), have been isolated from an Okinawan marine sponge Amphimedon species. The structures and stereochemistry of 1 and 2 were elucidated from the spectroscopic data and conformational analysis. Zamamidines A (1) and B (2) are the first manzamine alkaloids possessing a second //-carboline ring via an ethylene unit at N-2 of manzamine H and 1,2,3,4-tetrahydromanzamine B, respectively.",

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AU - Takahashi, Yohei

AU - Kubota, Takaaki

AU - Fromont, Jane

AU - Kobayashi, Jun'ichi

PY - 2009/1/1

Y1 - 2009/1/1

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AB - New manzamine alkaloids, zamamidines A (1) and B (2), have been isolated from an Okinawan marine sponge Amphimedon species. The structures and stereochemistry of 1 and 2 were elucidated from the spectroscopic data and conformational analysis. Zamamidines A (1) and B (2) are the first manzamine alkaloids possessing a second //-carboline ring via an ethylene unit at N-2 of manzamine H and 1,2,3,4-tetrahydromanzamine B, respectively.

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Zamamidines A and B, new manzamine alkaloids from the sponge Amphimedon species

Abstract

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