Zygomycotic invasion of the central nervous system

Tomoaki Sasaki, Masayuki Mineta, Keigo Kobayashi, Masakatsu Ando, Masahiko Obata

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)


Zygomycosis is an opportunistic fungal infection that affects the central nervous system (CNS). In this report, we present three cases of zygomycosis with CNS involvement. In two patients zygomycosis developed after neurosurgery, and in the third patient zygomycosis developed after bone marrow transplantation for leukemia. All patients developed persistent fever and neurological deficits. They presented with progressive cerebral infarction accompanied by hemorrhage. Intraoperative findings and histopathological examinations revealed that zygomycotic hyphae caused mycotic aneurysm, vasculitis, and venous occlusion.

Original languageEnglish
Pages (from-to)376-380
Number of pages5
JournalJapanese Journal of Radiology
Issue number5
Publication statusPublished - Jun 2010
Externally publishedYes


  • CNS invasion
  • Venous occlusion
  • Zygomycosis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging


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