Atsushi Fujimura

2023

CDKAL1 Drives the Maintenance of Cancer Stem-Like Cells by Assembling the eIF4F Translation Initiation Complex

Huang, R., Yamamoto, T., Nakata, E., Ozaki, T., Kurozumi, K., Wei, F., Tomizawa, K. & Fujimura, A., 2023, (Accepted/In press) In: Advanced Science.

研究成果 › 査読

Open Access

Particle and Heavy Ion Transport Code System-Based Microdosimetry for the Development of Boron Agents for Boron Neutron Capture Therapy

Shigehira, T., Hanafusa, T., Igawa, K., Kasai, T., Furuya, S., Nishimori, H., Maeda, Y., Michiue, H. & Fujimura, A., 2023, (Accepted/In press) In: Advanced Theory and Simulations.

研究成果 › 査読

2021

Adrenergic signaling promotes the expansion of cancer stem-like cells of malignant peripheral nerve sheath tumors

Huang, R., Fujimura, A., Nakata, E., Takihira, S., Inoue, H., Yoshikawa, S., Hiyama, T., Ozaki, T. & Kamiya, A., 6月 11 2021, In: Biochemical and Biophysical Research Communications. 557, p. 199-205 7 p.

研究成果 › 査読

Open Access

1 被引用数 (Scopus)

Differentiated glioblastoma cells accelerate tumor progression by shaping the tumor microenvironment via CCN1-mediated macrophage infiltration

Uneda, A., Kurozumi, K., Fujimura, A., Fujii, K., Ishida, J., Shimazu, Y., Otani, Y., Tomita, Y., Hattori, Y., Matsumoto, Y., Tsuboi, N., Makino, K., Hirano, S., Kamiya, A. & Date, I., 12月 2021, In: Acta Neuropathologica Communications. 9, 1, 29.

研究成果 › 査読

Open Access

21 被引用数 (Scopus)

Self-assembling A6K peptide nanotubes as a mercaptoundecahydrododecaborate (BSH) delivery system for boron neutron capture therapy (BNCT)

Michiue, H., Kitamatsu, M., Fukunaga, A., Tsuboi, N., Fujimura, A., Matsushita, H., Igawa, K., Kasai, T., Kondo, N., Matsui, H. & Furuya, S., 2月 10 2021, In: Journal of Controlled Release. 330, p. 788-796 9 p.

研究成果 › 査読

Open Access

12 被引用数 (Scopus)

Single-cell analyses reveal YAP/TAZ as regulators of stemness and cell plasticity in glioblastoma

Castellan, M., Guarnieri, A., Fujimura, A., Zanconato, F., Battilana, G., Panciera, T., Sladitschek, H. L., Contessotto, P., Citron, A., Grilli, A., Romano, O., Bicciato, S., Fassan, M., Porcù, E., Rosato, A., Cordenonsi, M. & Piccolo, S., 2月 2021, In: Nature Cancer. 2, 2, p. 174-188 15 p.

研究成果 › 査読

47 被引用数 (Scopus)

2020

Annexin A2-STAT3-Oncostatin M receptor axis drives phenotypic and mesenchymal changes in glioblastoma

Matsumoto, Y., Ichikawa, T., Kurozumi, K., Otani, Y., Fujimura, A., Fujii, K., Tomita, Y., Hattori, Y., Uneda, A., Tsuboi, N., Kaneda, K., Makino, K. & Date, I., 4月 5 2020, In: Acta Neuropathologica Communications. 8, 1, 42.

研究成果 › 査読

Open Access

13 被引用数 (Scopus)

In Vitro Studies to Define the Cell-Surface and Intracellular Targets of Polyarginine-Conjugated Sodium Borocaptate as a Potential Delivery Agent for Boron Neutron Capture Therapy

Fujimura, A., Yasui, S., Igawa, K., Ueda, A., Watanabe, K., Hanafusa, T., Ichikawa, Y., Yoshihashi, S., Tsuchida, K., Kamiya, A. & Furuya, S., 9月 23 2020, In: Cells. 9, 10

研究成果 › 査読

Open Access

10 被引用数 (Scopus)

2019

2-Methylthio Conversion of N6-Isopentenyladenosine in Mitochondrial tRNAs by CDK5RAP1 Promotes the Maintenance of Glioma-Initiating Cells

Yamamoto, T., Fujimura, A., Wei, F. Y., Shinojima, N., Kuroda, J. I., Mukasa, A. & Tomizawa, K., 11月 22 2019, In: iScience. 21, p. 42-56 15 p.

研究成果 › 査読

Open Access

10 被引用数 (Scopus)

2018

Defective Mitochondrial tRNA Taurine Modification Activates Global Proteostress and Leads to Mitochondrial Disease

Fakruddin, M., Wei, F. Y., Suzuki, T., Asano, K., Kaieda, T., Omori, A., Izumi, R., Fujimura, A., Kaitsuka, T., Miyata, K., Araki, K., Oike, Y., Scorrano, L., Suzuki, T. & Tomizawa, K., 2018, In: Cell Reports. 22, 2, p. 482-496 15 p.

研究成果 › 査読

61 被引用数 (Scopus)

2017

Reactive sulfur species regulate tRNA methylthiolation and contribute to insulin secretion

Takahashi, N., Wei, F. Y., Watanabe, S., Hirayama, M., Ohuchi, Y., Fujimura, A., Kaitsuka, T., Ishii, I., Sawa, T., Nakayama, H., Akaike, T. & Tomizawa, K., 1月 9 2017, In: Nucleic acids research. 45, 1, p. 435-445 11 p.

研究成果 › 査読

38 被引用数 (Scopus)

2016

Fluvoxamine, an anti-depressant, inhibits human glioblastoma invasion by disrupting actin polymerization

Hayashi, K., Michiue, H., Yamada, H., Takata, K., Nakayama, H., Wei, F. Y., Fujimura, A., Tazawa, H., Asai, A., Ogo, N., Miyachi, H., Nishiki, T., Tomizawa, K., Takei, K. & Matsui, H., 3月 18 2016, In: Scientific reports. 6, 23372.

研究成果 › 査読

38 被引用数 (Scopus)

HDAC9 regulates the alternative lengthening of telomere (ALT) pathway via the formation of ALT-associated PML bodies

Jamiruddin, M. R., Kaitsuka, T., Hakim, F., Fujimura, A., Wei, F. Y., Saitoh, H. & Tomizawa, K., 12月 2 2016, In: Biochemical and Biophysical Research Communications. 481, 1-2, p. 25-30 6 p.

研究成果 › 査読

9 被引用数 (Scopus)

Induction of Expandable Tissue-Specific Stem/Progenitor Cells through Transient Expression of YAP/TAZ

Panciera, T., Azzolin, L., Fujimura, A., Di Biagio, D., Frasson, C., Bresolin, S., Soligo, S., Basso, G., Bicciato, S., Rosato, A., Cordenonsi, M. & Piccolo, S., 12月 1 2016, In: Cell stem cell. 19, 6, p. 725-737 13 p.

研究成果 › 査読

Open Access

162 被引用数 (Scopus)

Mtu1-Mediated Thiouridine Formation of Mitochondrial tRNAs Is Required for Mitochondrial Translation and Is Involved in Reversible Infantile Liver Injury

Wu, Y., Wei, F. Y., Kawarada, L., Suzuki, T., Araki, K., Komohara, Y., Fujimura, A., Kaitsuka, T., Takeya, M., Oike, Y., Suzuki, T. & Tomizawa, K., 9月 2016, In: PLoS genetics. 12, 9, e1006355.

研究成果 › 査読

22 被引用数 (Scopus)

2015

Cdk5rap1-mediated 2-methylthio modification of mitochondrial tRNAs governs protein translation and contributes to myopathy in mice and humans

Wei, F. Y., Zhou, B., Suzuki, T., Miyata, K., Ujihara, Y., Horiguchi, H., Takahashi, N., Xie, P., Michiue, H., Fujimura, A., Kaitsuka, T., Matsui, H., Koga, Y., Mohri, S., Suzuki, T., Oike, Y. & Tomizawa, K., 3月 3 2015, In: Cell Metabolism. 21, 3, p. 428-442 15 p.

研究成果 › 査読

76 被引用数 (Scopus)

2014

Identification of a splicing variant that regulates type 2 diabetes risk factor CDKAL1 level by a coding-independent mechanism in human

Zhou, B., Wei, F. Y., Kanai, N., Fujimura, A., Kaitsuka, T. & Tomizawa, K., 9月 2014, In: Human Molecular Genetics. 23, 17, p. 4639-4650 12 p., ddu184.

研究成果 › 査読

37 被引用数 (Scopus)

2013

Cyclin G2 promotes hypoxia-driven local invasion of glioblastoma by orchestrating cytoskeletal dynamics

Fujimura, A., Hiroyuki, M., Cheng, Y., Uneda, A., Tani, Y., Nishiki, T., Ichikawa, T., Wei, F. Y., Tomizawa, K. & Matsui, H., 11月 2013, In: Neoplasia (United States). 15, 11, p. 1272-1281 10 p.

研究成果 › 査読

22 被引用数 (Scopus)

2012

A protein transduction method using oligo-arginine (3R) for the delivery of transcription factors into cell nuclei

Hitsuda, T., Michiue, H., Kitamatsu, M., Fujimura, A., Wang, F., Yamamoto, T., Han, X. J., Tazawa, H., Uneda, A., Ohmori, I., Nishiki, T., Tomizawa, K. & Matsui, H., 6月 2012, In: Biomaterials. 33, 18, p. 4665-4672 8 p.

研究成果 › 査読

30 被引用数 (Scopus)

Ca ²⁺-independent syntaxin binding to the C ₂B effector region of synaptotagmin

Masumoto, T., Suzuki, K., Ohmori, I., Michiue, H., Tomizawa, K., Fujimura, A., Nishiki, T. & Matsui, H., 1月 2012, In: Molecular and Cellular Neuroscience. 49, 1, p. 1-8 8 p.

研究成果 › 査読

10 被引用数 (Scopus)

Clinicopathological characteristics of human epidermal growth factor receptor 2-positive Barrett's adenocarcinoma

Tanaka, T., Fujimura, A., Ichimura, K., Yanai, H., Sato, Y., Takata, K., Okada, H., Kawano, S., Tanabe, S. & Yoshino, T., 2012, In: World journal of gastroenterology. 18, 43, p. 6263-6268 6 p.

研究成果 › 査読

7 被引用数 (Scopus)

Combining poly-arginine with the hydrophobic counter-anion 4-(1-pyrenyl)-butyric acid for protein transduction in transdermal delivery

Candan, G., Michiue, H., Ishikawa, S., Fujimura, A., Hayashi, K., Uneda, A., Mori, A., Ohmori, I., Nishiki, T., Matsui, H. & Tomizawa, K., 9月 2012, In: Biomaterials. 33, 27, p. 6468-6475 8 p.

研究成果 › 査読

34 被引用数 (Scopus)

2011

Deficit of tRNA^Lys modification by Cdkal1 causes the development of type 2 diabetes in mice

Wei, F. Y., Suzuki, T., Watanabe, S., Kimura, S., Kaitsuka, T., Fujimura, A., Matsui, H., Atta, M., Michiue, H., Fontecave, M., Yamagata, K., Suzuki, T. & Tomizawa, K., 9月 1 2011, In: Journal of Clinical Investigation. 121, 9, p. 3598-3608 11 p.

研究成果 › 査読

193 被引用数 (Scopus)

Expression of a constitutively active calcineurin encoded by an intron-retaining mRNA in follicular keratinocytes

Fujimura, A., Michiue, H., Nishiki, T., Ohmori, I., Wei, F. Y., Matsui, H. & Tomizawa, K., 2011, In: PloS one. 6, 3, e17685.

研究成果 › 査読

10 被引用数 (Scopus)

2009

Delivery of sodium borocaptate to glioma cells using immunoliposome conjugated with anti-EGFR antibodies by ZZ-His

Feng, B., Tomizawa, K., Michiue, H., Miyatake, S. I., Han, X. J., Fujimura, A., Seno, M., Kirihata, M. & Matsui, H., 3月 2009, In: Biomaterials. 30, 9, p. 1746-1755 10 p.

研究成果 › 査読

88 被引用数 (Scopus)

Atsushi Fujimura

研究成果

検索結果