Emilio satoshi Hara

2023

Variable Stiffness Actuators with Covalently Attached Nanofragments that Induce Mineralization

Cao, D., Martinez, J. G., Hara, E. S. & Jager, E. W. H., 2023, (Accepted/In press) In: Advanced Materials Technologies.

研究成果 › 査読

Open Access

2022

Biohybrid Variable-Stiffness Soft Actuators that Self-Create Bone

Cao, D., Martinez, J. G., Hara, E. S. & Jager, E. W. H., 2月 24 2022, In: Advanced Materials. 34, 8, 2107345.

研究成果 › 査読

Open Access

5 被引用数 (Scopus)

Distinct Morphologies of Bone Apatite Clusters in Endochondral and Intramembranous Ossification

Hara, E. S., Nagaoka, N., Okada, M., Nakano, T. & Matsumoto, T., 2022, (Accepted/In press) In: Advanced Biology.

研究成果 › 査読

1 被引用数 (Scopus)

Important roles of odontoblast membrane phospholipids in early dentin mineralization

Anada, R., Hara, E. S., Nagaoka, N., Okada, M., Kamioka, H. & Matsumoto, T., 2022, (Accepted/In press) In: Journal of Materials Chemistry B.

研究成果 › 査読

Open Access

Mechanotransductive Mechanisms of Biomimetic Hydrogel Cues Modulating Meckel's Cartilage Degeneration

Farahat, M., Hara, E. S., Anada, R., Kazi, G. A. S., Akhter, N. M. & Matsumoto, T., 2022, (Accepted/In press) In: Advanced Biology.

研究成果 › 査読

Preclinical bioequivalence study of E.coli-derived rhBMP-2/β-TCP and autogenous bone in a canine guided-bone regeneration model

Nosho, S., Ono, M., Komori, T., Mikai, A., Tosa, I., Ishibashi, K., Tanaka, Y., Kimura-Ono, A., Hara, E. S., Oohashi, T. & Kuboki, T., 2022, In: Journal of Prosthodontic Research. 66, 1, p. 124-130 7 p.

研究成果 › 査読

Open Access

2 被引用数 (Scopus)

Self-adhering implantable device of titanium: Enhanced soft-tissue adhesion by sandblast pretreatment

Yabe, A., Okada, M., Hara, E. S., Torii, Y. & Matsumoto, T., 3月 2022, In: Colloids and Surfaces B: Biointerfaces. 211, 112283.

研究成果 › 査読

2 被引用数 (Scopus)

2021

Effect of Biomechanical Environment on Degeneration of Meckel’s Cartilage

Farahat, M., Kazi, G. A. S., Hara, E. S. & Matsumoto, T., 2月 2021, In: Journal of dental research. 100, 2, p. 171-178 8 p.

研究成果 › 査読

1 被引用数 (Scopus)

Immediate soft-tissue adhesion and the mechanical properties of the Ti-6Al-4V alloy after long-term acid treatment

Wang, Y., Okada, M., Xie, S. C., Jiao, Y. Y., Hara, E. S., Yanagimoto, H., Fukumoto, T. & Matsumoto, T., 10月 21 2021, In: Journal of Materials Chemistry B. 9, 39, p. 8348-8354 7 p.

研究成果 › 査読

4 被引用数 (Scopus)

Nanostructural analysis of distinct nucleation sites in pathological mineralization

Hara, E. S., Oozawa, S., Nagaoka, N., Okada, M., Kasahara, S. & Matsumoto, T., 7月 7 2021, In: Materials Advances. 2, 13, p. 4423-4431 9 p.

研究成果 › 査読

Open Access

1 被引用数 (Scopus)

Suppression of bone necrosis around tooth extraction socket in a mronj-like mouse model by e-rhbmp-2 containing artificial bone graft administration

Tanaka, Y., Aung, K. T., Ono, M., Mikai, A., Dang, A. T., Hara, E. S., Tosa, I., Ishibashi, K., Ono-Kimura, A., Nawachi, K., Kuboki, T. & Oohashi, T., 12月 1 2021, In: International journal of molecular sciences. 22, 23, 12823.

研究成果 › 査読

Open Access

1 被引用数 (Scopus)

Tryptophan and kynurenine enhances the stemness and osteogenic differentiation of bone marrow-derived mesenchymal stromal cells in vitro and in vivo

Pham, H. T., Ono, M., Hara, E. S., Nguyen, H. T. T., Dang, A. T., Do, H. T., Komori, T., Tosa, I., Hazehara-Kunitomo, Y., Yoshioka, Y., Oida, Y., Akiyama, K. & Kuboki, T., 1月 1 2021, In: Materials. 14, 1, p. 1-15 15 p., 208.

研究成果 › 査読

Open Access

3 被引用数 (Scopus)

2020

Aging-affected msc functions and severity of periodontal tissue destruction in a ligature-induced mouse periodontitis model

Aung, K. T., Akiyama, K., Kunitomo, M., Mun, A. Y., Tosa, I., Nguyen, H. T. T., Zhang, J., Kohno, T., Ono, M., Hara, E. S. & Kuboki, T., 11月 1 2020, In: International journal of molecular sciences. 21, 21, p. 1-20 20 p., 8103.

研究成果 › 査読

Open Access

15 被引用数 (Scopus)

Association of masticatory muscle activity with sleep arousal and other concomitant movements during sleep

Miki, H., Minakuchi, H., Miyagi, M., Hara, E. S., Shigemoto, S., Suzuki, Y., Maekawa, K., Matsuka, Y., Clark, G. T. & Kuboki, T., 3月 1 2020, In: Journal of oral rehabilitation. 47, 3, p. 281-288 8 p.

研究成果 › 査読

5 被引用数 (Scopus)

BMP-2/Β-TCP local delivery for bone regeneration in MRONJ-like mouse model

Mikai, A., Ono, M., Tosa, I., Nguyen, H. T. T., Hara, E. S., Nosho, S., Kimura-Ono, A., Nawachi, K., Takarada, T., Kuboki, T. & Oohashi, T., 10月 1 2020, In: International journal of molecular sciences. 21, 19, p. 1-13 13 p., 7028.

研究成果 › 査読

Open Access

15 被引用数 (Scopus)

Cellular fragments as biomaterial for rapid in vitro bone-like tissue synthesis

Akhter, M. N., Hara, E. S., Kadoya, K., Okada, M. & Matsumoto, T., 8月 1 2020, In: International journal of molecular sciences. 21, 15, p. 1-17 17 p., 5327.

研究成果 › 査読

Open Access

3 被引用数 (Scopus)

Distinct osteogenic potentials of BMP-2 and FGF-2 in extramedullary and medullary microenvironments

Nosho, S., Tosa, I., Ono, M., Hara, E. S., Ishibashi, K., Mikai, A., Tanaka, Y., Kimura-Ono, A., Komori, T., Maekawa, K., Kuboki, T. & Oohashi, T., 11月 1 2020, In: International journal of molecular sciences. 21, 21, p. 1-14 14 p., 7967.

研究成果 › 査読

Open Access

8 被引用数 (Scopus)

DNA Methylation-Based Regulation of Human Bone Marrow-Derived Mesenchymal Stem/Progenitor Cell Chondrogenic Differentiation

Nomura, Y., Hara, E. S., Yoshioka, Y., Nguyen, H. T., Nosho, S., Komori, T., Ishibashi, K., Oohashi, T., Ono, M. & Kuboki, T., 1月 1 2020, In: Cells Tissues Organs. 207, 3-4, p. 115-126 12 p.

研究成果 › 査読

7 被引用数 (Scopus)

Titanium as an Instant Adhesive for Biological Soft Tissue

Okada, M., Hara, E. S., Yabe, A., Okada, K., Shibata, Y., Torii, Y., Nakano, T. & Matsumoto, T., 5月 1 2020, In: Advanced Materials Interfaces. 7, 9, 1902089.

研究成果 › 査読

Open Access

7 被引用数 (Scopus)

Vibratory splint therapy for decreasing sleep clenching: A pilot study

Hara, E. S., Witzel, A. L., Minakuchi, H., de Pitta, C. E., Gallo, R. T., Okada, M., Matsumoto, T., Kuboki, T. & Bolzan, M. C., 1月 2 2020, In: Cranio - Journal of Craniomandibular Practice. 38, 1, p. 15-21 7 p.

研究成果 › 査読

1 被引用数 (Scopus)

2019

Acidic pre-conditioning enhances the stem cell phenotype of human bone marrow stem/progenitor cells

Hazehara-Kunitomo, Y., Hara, E. S., Ono, M., Aung, K. T., Komi, K., Pham, H. T., Akiyama, K., Okada, M., Oohashi, T., Matsumoto, T. & Kuboki, T., 3月 1 2019, In: International journal of molecular sciences. 20, 5, 1097.

研究成果 › 査読

Open Access

21 被引用数 (Scopus)

Biomimetic mineralization using matrix vesicle nanofragments

Kunitomi, Y., Hara, E. S., Okada, M., Nagaoka, N., Kuboki, T., Nakano, T., Kamioka, H. & Matsumoto, T., 5月 2019, In: Journal of Biomedical Materials Research - Part A. 107, 5, p. 1021-1030 10 p.

研究成果 › 査読

Open Access

15 被引用数 (Scopus)

Bone Marrow Cells Inhibit BMP-2-Induced Osteoblast Activity in the Marrow Environment

Nguyen, H. T., Ono, M., Oida, Y., Hara, E. S., Komori, T., Akiyama, K., Nguyen, H. T. T., Aung, K. T., Pham, H. T., Tosa, I., Takarada, T., Matsuo, K., Mizoguchi, T., Oohashi, T. & Kuboki, T., 2月 2019, In: Journal of Bone and Mineral Research. 34, 2, p. 327-332 6 p.

研究成果 › 査読

12 被引用数 (Scopus)

Fibronectin-induced ductal formation in salivary gland self-organization model

Farahat, M., Kazi, G. A. S., Taketa, H., Hara, E. S., Oshima, M., Kuboki, T. & Matsumoto, T., 9月 1 2019, In: Developmental Dynamics. 248, 9, p. 813-825 13 p.

研究成果 › 査読

9 被引用数 (Scopus)

Improvement of mechanical properties of Y-TZP by thermal annealing with monoclinic zirconia nanoparticle coating

Okada, M., Taketa, H., Hara, E. S., Torii, Y., Irie, M. & Matsumoto, T., 7月 2019, In: Dental Materials. 35, 7, p. 970-978 9 p.

研究成果 › 査読

5 被引用数 (Scopus)

Intermediate water on calcium phosphate minerals: ITS origin and role in crystal growth

Okada, M., Hara, E. S., Kobayashi, D., Kai, S., Ogura, K., Tanaka, M. & Matsumoto, T., 3月 2019, In: ACS Applied Bio Materials. 2, 3, p. 981-986 6 p.

研究成果 › 査読

14 被引用数 (Scopus)

Type XVIII collagen modulates keratohyalin granule formation and keratinization in oral mucosa

Nguyen, H. T. T., Ono, M., Hara, E. S., Komori, T., Edamatsu, M., Yonezawa, T., Kimura-Ono, A., Maekawa, K., Kuboki, T. & Oohashi, T., 10月 1 2019, In: International journal of molecular sciences. 20, 19, 4739.

研究成果 › 査読

Open Access

2 被引用数 (Scopus)

2018

Bioinspired Mineralization Using Chondrocyte Membrane Nanofragments

Hara, E. S., Okada, M., Nagaoka, N., Hattori, T., Kuboki, T., Nakano, T. & Matsumoto, T., 2月 12 2018, In: ACS Biomaterials Science and Engineering. 4, 2, p. 617-625 9 p.

研究成果 › 査読

20 被引用数 (Scopus)

CCN4/WISP1 controls cutaneous wound healing by modulating proliferation, migration and ECM expression in dermal fibroblasts via α5β1 and TNFα

Ono, M., Masaki, A., Maeda, A., Kilts, T. M., Hara, E. S., Komori, T., Pham, H., Kuboki, T. & Young, M. F., 8月 2018, In: Matrix Biology. 68-69, p. 533-546 14 p.

研究成果 › 査読

47 被引用数 (Scopus)

Chondrocyte burst promotes space for mineral expansion

Hara, E. S., Okada, M., Nagaoka, N., Hattori, T., Iida, L. M., Kuboki, T., Nakano, T. & Matsumoto, T., 1月 2018, In: Integrative Biology (United Kingdom). 10, 1, p. 57-66 10 p.

研究成果 › 査読

11 被引用数 (Scopus)

Rapid bioinspired mineralization using cell membrane nanofragments and alkaline milieu

Hara, E. S., Okada, M., Kuboki, T., Nakano, T. & Matsumoto, T., 2018, In: Journal of Materials Chemistry B. 6, 38, p. 6153-6161 9 p.

研究成果 › 査読

11 被引用数 (Scopus)

Type IV collagen α6 chain is a regulator of keratin 10 in keratinization of oral mucosal epithelium

Komori, T., Ono, M., Hara, E. S., Ueda, J., Nguyen, H. T. T., Nguyen, H. T., Yonezawa, T., Maeba, T., Kimura-Ono, A., Takarada, T., Momota, R., Maekawa, K., Kuboki, T. & Oohashi, T., 12月 1 2018, In: Scientific reports. 8, 1, 2612.

研究成果 › 査読

14 被引用数 (Scopus)

2017

Biocompatible nanostructured solid adhesives for biological soft tissues

Okada, M., Nakai, A., Hara, E. S., Taguchi, T., Nakano, T. & Matsumoto, T., 7月 15 2017, In: Acta Biomaterialia. 57, p. 404-413 10 p.

研究成果 › 査読

19 被引用数 (Scopus)

MCSF orchestrates branching morphogenesis in developing submandibular gland tissue

Sathi, G. A., Farahat, M., Hara, E. S., Taketa, H., Nagatsuka, H., Kuboki, T. & Matsumoto, T., 5月 1 2017, In: Journal of cell science. 130, 9, p. 1559-1569 11 p.

研究成果 › 査読

15 被引用数 (Scopus)

MSCs feeder layers induce SMG selforganization and branching morphogenesis

Farahat, M., Sathi, G. A., Hara, E. S., Taketa, H., Kuboki, T. & Matsumoto, T., 4月 2017, In: PloS one. 12, 4, e0176453.

研究成果 › 査読

7 被引用数 (Scopus)

Practical whole-tooth restoration utilizing autologous bioengineered tooth germ transplantation in a postnatal canine model

Ono, M., Oshima, M., Ogawa, M., Sonoyama, W., Satoshi Hara, E., Oida, Y., Shinkawa, S., Nakajima, R., Mine, A., Hayano, S., Fukumoto, S., Kasugai, S., Yamaguchi, A., Tsuji, T. & Kuboki, T., 3月 16 2017, In: Scientific reports. 7, 44522.

研究成果 › 査読

45 被引用数 (Scopus)

2016

Antagonistic effects of insulin and TGF-β3 during chondrogenic differentiation of human BMSCs under a minimal amount of factors

Hara, E. S., Ono, M., Yoshioka, Y., Ueda, J., Hazehara, Y., Pham, H. T., Matsumoto, T. & Kuboki, T., 3月 1 2016, In: Cells Tissues Organs. 201, 2, p. 88-96 9 p.

研究成果 › 査読

8 被引用数 (Scopus)

CCN4/WISP-1 positively regulates chondrogenesis by controlling TGF-β3 function

Yoshioka, Y., Ono, M., Maeda, A., Kilts, T. M., Hara, E. S., Khattab, H., Ueda, J., Aoyama, E., Oohashi, T., Takigawa, M., Young, M. F. & Kuboki, T., 2月 1 2016, In: Bone. 83, p. 162-170 9 p.

研究成果 › 査読

20 被引用数 (Scopus)

Sleep bruxism frequency and platelet serotonin transporter activities in young adult subjects

Minakuchi, H., Sogawa, C., Miki, H., Hara, E. S., Maekawa, K., Sogawa, N., Kitayama, S., Matsuka, Y., Clark, G. T. & Kuboki, T., 3月 1 2016, In: Sleep and Breathing. 20, 1, p. 271-276 6 p.

研究成果 › 査読

5 被引用数 (Scopus)

2015

A longitudinal retrospective study of the analysis of the risk factors of implant failure by the application of generalized estimating equations

Noda, K., Arakawa, H., Kimura-Ono, A., Yamazaki, S., Hara, E. S., Sonoyama, W., Maekawa, K., Okura, K., Shintani, A., Matsuka, Y. & Kuboki, T., 7月 1 2015, In: Journal of Prosthodontic Research. 59, 3, p. 178-184 7 p.

研究成果 › 査読

41 被引用数 (Scopus)

A risk factor analysis of accumulated postoperative pain and swelling sensation after dental implant surgery using a cellular phone-based real-time assessment

Kuroi, R., Minakuchi, H., Hara, E. S., Kawakami, A., Maekawa, K., Okada, H. & Kuboki, T., 7月 1 2015, In: Journal of Prosthodontic Research. 59, 3, p. 194-198 5 p.

研究成果 › 査読

13 被引用数 (Scopus)

Fluocinolone acetonide is a potent synergistic factor of TGF-β3-associated chondrogenesis of bone marrow-derived mesenchymal stem cells for articular surface regeneration

Hara, E. S., Ono, M., Pham, H. T., Sonoyama, W., Kubota, S., Takigawa, M., Matsumoto, T., Young, M. F., Olsen, B. R. & Kuboki, T., 9月 1 2015, In: Journal of Bone and Mineral Research. 30, 9, p. 1585-1596 12 p.

研究成果 › 査読

27 被引用数 (Scopus)

In silico comparison of the reproducibility of full-arch implant provisional restorations to final restoration between a 3D Scan/CAD/CAM technique and the conventional method

Mino, T., Maekawa, K., Ueda, A., Higuchi, S., Sejima, J., Takeuchi, T., Hara, E. S., Kimura-Ono, A., Sonoyama, W. & Kuboki, T., 4月 1 2015, In: Journal of Prosthodontic Research. 59, 2, p. 152-158 7 p.

研究成果 › 査読

16 被引用数 (Scopus)

2014

A short-term treatment with tumor necrosis factor-alpha enhances stem cell phenotype of human dental pulp cells

Ueda, M., Fujisawa, T., Ono, M., Hara, E. S., Pham, H. T., Nakajima, R., Sonoyama, W. & Kuboki, T., 2月 28 2014, In: Stem Cell Research and Therapy. 5, 1, 31.

研究成果 › 査読

37 被引用数 (Scopus)

Comparison of platelet serotonin transporter activity in subjects with severe sleep bruxism and control

Minakuchi, H., Sogawa, C., Hara, E. S., Miki, H., Maekawa, K., Sogawa, N., Kitayama, S., Matsuka, Y., Clark, G. T. & Kuboki, T., 2014, In: Journal of Prosthodontic Research. 58, 4, p. 217-222 6 p.

研究成果 › 査読

6 被引用数 (Scopus)

Efficient bone formation in a swine socket lift model using escherichia coli-derived recombinant human bone morphogenetic protein-2 adsorbed in β-tricalcium phosphate

Ono, M., Sonoyama, W., Yamamoto, K., Oida, Y., Akiyama, K., Shinkawa, S., Nakajima, R., Pham, H. T., Hara, E. S. & Kuboki, T., 2月 24 2014, In: Cells Tissues Organs. 199, 4, p. 249-255 7 p.

研究成果 › 査読

11 被引用数 (Scopus)

Mesenchymal stem/progenitor cell isolation from tooth extraction sockets

Nakajima, R., Ono, M., Hara, E. S., Oida, Y., Shinkawa, S., Pham, H. T., Akiyama, K., Sonoyama, W., Maekawa, K. & Kuboki, T., 11月 11 2014, In: Journal of dental research. 93, 11, p. 1133-1140 8 p.

研究成果 › 査読

31 被引用数 (Scopus)

Regeneration of calvarial defects with escherichia coli-derived rhBMP-2 adsorbed in PLGA Membrane

Ono, M., Sonoyama, W., Nema, K., Hara, E. S., Oida, Y., Pham, H. T., Yamamoto, K., Hirota, K., Sugama, K., Sebald, W. & Kuboki, T., 2014, In: Cells Tissues Organs. 198, 5, p. 367-376 10 p.

研究成果 › 査読

12 被引用数 (Scopus)

The regenerative effects of CCN2 independent modules on chondrocytes in vitro and osteoarthritis models in vivo

Abd El Kader, T., Kubota, S., Nishida, T., Hattori, T., Aoyama, E., Janune, D., Hara, E. S., Ono, M., Tabata, Y., Kuboki, T. & Takigawa, M., 2月 2014, In: Bone. 59, p. 180-188 9 p.

研究成果 › 査読

28 被引用数 (Scopus)

2013

A novel vibratory stimulation-based occlusal splint for alleviation of TMD painful symptoms: A pilot study

Hara, E. S., Witzel, A. L., de Luca, C. E. P., Ballester, R. Y., Kuboki, T. & Bolzan, M. C., 3月 2013, In: Journal of oral rehabilitation. 40, 3, p. 179-184 6 p.

研究成果 › 査読

6 被引用数 (Scopus)

Emilio satoshi Hara

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Emilio　satoshi Hara